Results 61 to 70 of about 1,625,324 (292)

Overcoming the acoustic diffraction limit in photoacoustic imaging by localization of flowing absorbers

, 2017
The resolution of photoacoustic imaging deep inside scattering media is limited by the acoustic diffraction limit. In this work, taking inspiration from super-resolution imaging techniques developed to beat the optical diffraction limit, we demonstrate ...
Arnal, Bastien, Bossy, Emmanuel, Vilov, Sergey   +2 more
core   +3 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Fluorescence monitoring of capilarry electrophoresis separation in a lab-on-a-chip with monolithically integrated waveguides [PDF]

, 2008
Femtosecond-laser-written optical waveguides were monolithically integrated into a commercial lab-on-a-chip to intersect a microfluidic channel. Laser excitation through these waveguides confines the excitation window to a width of 12 μm, enabling high ...
Besselink, G.A.J., Cerullo, G., Dekker, R., Dongre, C., Hoekstra, H.J.W.M., Martinez-Vazquez, R., Osellame, R., Pollnau, M., Ramponi, R., Vlekkert, H.H. van den, Weeghel, R. van   +10 more
core   +1 more source

A High Resolution Vernier Digital-to-Time Converter Implemented with 65 nm FPGA

Applied Sciences, 2019
In this paper, a digital-to-time converter (DTC) based on the three delay lines (3D) Vernier principle is proposed and implemented with field programmable gate arrays (FPGAs).
Chenggang Yan, Chen Hu, Jianhui Wu
doaj   +1 more source

α-Quasi-Lock Semantic Resolution Method Based on Lattice-Valued Logic [PDF]

International Journal of Computational Intelligence Systems, 2014
Based on the general form of α-resolution principle for a lattice-valued logic with truth-values defined in a lattice-valued logical algebra structure - lattice implication algebra, the further extended α-resolution method in this lattice ...
Xiaomei Zhong, Yang Xu, Jun Liu, Shuwei Chen   +3 more
doaj   +1 more source

Resolution and the binary encoding of combinatorial principles

, 2018
We investigate the size complexity of proofs in $Res(s)$ -- an extension of Resolution working on $s$-DNFs instead of clauses -- for families of contradictions given in the {\em unusual binary} encoding. A motivation of our work is size lower bounds of refutations in Resolution for families of contradictions in the usual unary encoding.
Dantchev S., Galesi N., Martin B.
openaire   +5 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Resolution Enhancement for Low-resolution Text Images Using Generative Adversarial Network

MATEC Web of Conferences, 2018
In recent years, although Optical Character Recognition (OCR) has made considerable progress, low-resolution text images commonly appearing in many scenarios may still cause errors in recognition. For this problem, the technique of Generative Adversarial
Kong Jie, Wang Congying
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source