Results 161 to 170 of about 6,962 (307)

Robustly Linearized Model Predictive Control for Nonlinear Infinite-Dimensional Systems. [PDF]

open access: yesIFAC Pap OnLine, 2023
El-Kebir H   +3 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Pseudo-resolvent energy of weighted graphs

open access: yes
Let G be a finite order graph. Its resolvent matrix and its resolvent energy are respectively given by R xi ( A ( G )) = (A(G) - xi I)-1 -1 and ER ( G ) = Sigma n n i = 1 (n - lambda i)-1. i ) -1 . For some classes of weighted graphs, we know that lambda
Shukur, Ali A.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Furthering resolvent-based jet noise models

open access: yes, 2019
Resolvent analysis continues to provide promising results for modeling the hydrodynamic near-field and acoustic far-field in turbulent jets, particularly when compared to modes deduced through spectral proper orthogonal decomposition (SPOD) of high ...
Colonius, Tim, Pickering, Ethan M.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Separation of Time Scales in Weakly Interacting Diffusions. [PDF]

open access: yesArch Ration Mech Anal
Adams ZP, Engel M, Gvalani RS.
europepmc   +1 more source

Home - About - Disclaimer - Privacy