Results 281 to 290 of about 43,954 (320)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Surrogate Modeling of Resonant Behavior in Scattering Problems Through Adaptive Rational Approximation and Sketching. [PDF]

J Sci Comput
Pradovera D, Hiptmair R, Perugia I.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Sweat gland carcinoma with neuroendocrine differentiation of the scalp with elevated serum chromogranin A levels. [PDF]

JAAD Case Rep
Wyatt EC, Wyatt EL, Graham RL.
europepmc   +1 more source

Phase-lag mixed integral equation of a generalized symmetric potential kernel and its physical meanings in (3+1) dimensions. [PDF]

Heliyon
Jan AR.
europepmc   +1 more source

Magnetic Tunneling Between Disc-Shaped Obstacles. [PDF]

Commun Math Phys
Fournais S, Morin L.
europepmc   +1 more source

Distribution of centrality measures on undirected random networks via the cavity method. [PDF]

Proc Natl Acad Sci U S A
Bartolucci S, Caccioli F, Caravelli F, Vivo P.   +3 more
europepmc   +1 more source

Impedance and resolvent methods for calculating the shear waves spectra in 1D and 2D phononic waveguides

, 2014
Maria Korotyaeva
openalex   +1 more source