Results 51 to 60 of about 43,954 (320)
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
We say that a topological group $G$ is partially box $ $-resolvable if there exist a dense subset $B$ of $G$ and a subset $A $ of $G$, $|A|= $ such that the subsets $\{ aB: a\in A\}$ are pairwise disjoint. If $G=AB$ then $G$ is called box $ $-resolvable. We prove two theorems. If a topological group $G$ contains an injective convergent sequence then
openaire +2 more sources
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
A partial factorization of the powersum formula
For any univariate polynomial P whose coefficients lie in an ordinary differential field 𝔽 of characteristic zero, and for any constant indeterminate α, there exists a nonunique nonzero linear ordinary differential operator ℜ of finite order such that ...
John Michael Nahay
doaj +1 more source
Resolvability vs. almost resolvability
A space X is kappa-resolvable (resp. almost kappa-resolvable) if it contains kappa dense sets that are pairwise disjoint (resp. almost disjoint over the ideal of nowhere dense subsets of X). Answering a problem raised by Juhasz, Soukup, and Szentmiklossy, and improving a consistency result of Comfort and Hu, we prove, in ZFC, that for every infinite ...
Juhász, István +2 more
openaire +2 more sources
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Periodic solutions of Volterra integral equations
Consider the system of equationsx(t)=f(t)+∫−∞tk(t,s)x(s)ds, (1)andx(t)=f(t)+∫−∞tk(t,s)g(s,x(s))ds. (2)Existence of continuous periodic solutions of (1) is shown using the resolvent function of the kernel k.
M. N. Islam
doaj +1 more source
Resolvent estimates with mild trapping
We discuss recent progress in understanding the effects of certain trapping geometries on cut-off resolvent estimates, and thus on the qualititative behavior of linear evolution equations.
Wunsch, Jared
core +1 more source
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Electromagnetic fields calculation on the moving boundary of the medium irradiated by Airy pulse
Relevance. The new effects of electromagnetic pulse propagation obtained as a result of its interaction with a moving boundary can be actively used when pulses pass through various devices and equipment, such as lenses, mirrors, etc.
O.V. Zhyla, N.P. Stognii
doaj +1 more source

