Results 111 to 120 of about 22,026,600 (288)

Efficient harmonic resolvent analysis via time-stepping

We present an extension of the RSVD-$Δt$ algorithm initially developed for resolvent analysis of statistically stationary flows to handle harmonic resolvent analysis of time-periodic flows.
Jung, Junoh, Farghadan, Ali, Bhagwat, Rutvij, Towne, Aaron   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Resolvent analysis of turbulent pipe, channel and boundary layer flows

, 2023
Understanding the properties of coherent structures in wall-bounded turbulent flows is of great importance, as these structures are critical in determining the skin friction drag in the design of modern aircraft and ships [1].
Fu, Lin, Zhu, Wenkai
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Resolvent analysis for jet noise source identification

, 2018
We use resolvent analysis and spectral proper orthogonal decomposition (SPOD) to deduce the acoustic sources for an isothermal Mach 1.5 round jet. Both physics-based resolvent analysis and data-driven SPOD (using a high-fidelity, experimentally-verified,
Schmidt, Oliver T., Colonius, Tim, Rigas, Georgios, Pickering, Ethan M.   +3 more
core  

Resolvent Iterative Methods for Solving System of Extended General Variational Inclusions

Journal of Inequalities and Applications, 2011
We introduce and consider some new systems of extended general variational inclusions involving six different operators. We establish the equivalence between this system of extended general variational inclusions and the fixed points using the resolvent
Al-Said Eisa, Noor MuhammadAslam, Noor KhalidaInayat   +2 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Proportional-Arithmetic Framework for Fourier Analysis on the Positive Real Line

Axioms
This paper develops a Fourier framework internal to proportional arithmetic on the positive real line. We construct the corresponding complex scalar field, differential and integral operators, oscillatory kernel, Fourier transform, and proportional ...
Carlos M. Cruz-Rodas, Marlon M. López-Flores, William Campillay-Llanos   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source