Results 91 to 100 of about 1,236 (297)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Resolvent of matrix polynomials, pseudospectra and inversion problems [PDF]
, 2002 This paper deals with the mathematical model of a dynamic systems written by the n ordinary differential equations of order m with constant coefficients.
Kozanek, Jan
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The semiclassical resolvent on conformally compact manifolds with variable curvature at infinity [PDF]
, 2016 We construct a semiclassical parametrix for the resolvent of the Laplacian acting on functions on nontrapping conformally compact manifolds with variable sectional curvature at infinity.
Sá Barreto, Antônio, Wang, Yiran
core +1 more source
2×2 operator matrix with real parameter and its spectrum [PDF]
E3S Web of ConferencesIn the present paper we consider a linear bounded self-adjoint 2×2 block operator matrix Aμ (so called generalized Friedrichs model) with real parameter μ ∈ R.
Dilmurodov Elyor B. +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Resolvent and Scattering Matrix at the Maximum of the Potential [PDF]
, 2008 2000 Mathematics Subject Classification: 35P25, 81U20, 35S30, 47A10, 35B38.We study the microlocal structure of the resolvent of the semiclassical Schrödinger operator with short range potential at an energy which is a unique non-degenerate global ...
Ramond, Thierry +2 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Finite-dimensional approximations of the resolvent of an infinite band matrix and continued fractions [PDF]
, 1999 19 pages, no figures.-- MSC1991 codes: Primary 47B99, 47A10, 40A15; Secondary 30B70.-- Originally published in Russian language by the Russian Academy of Mathematics in: Matematicheskii Sbornik 190(4): 23–42 (1999).MR#: MR1702505 (2000e:47052)Zbl#: Zbl ...
López Lagomasino, Guillermo +3 more
core +1 more source
Eigenvalue estimates for the resolvent of a non-normal matrix [PDF]
Journal of Spectral Theory, 2015 We investigate the relation between the spectrum of a non-normal matrix and the norm of its resolvent. We provide spectral estimates for the resolvent of matrices whose largest singular value is bounded by 1 (so-called Hilbert space contractions) and for power-bounded matrices.
openaire +3 more sources