Results 61 to 70 of about 2,535,841 (289)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
On some local spectral theory and bounded local resolvent of operator matrices [PDF]
Mathematica Bohemica, 2018 We extend and generalize some results in local spectral theory for upper triangular operator matrices to upper triangular operator matrices with unbounded entries.
Abdelaziz Tajmouati +2 more
doaj +1 more source
On the equivalence between matrix riccati equations and Fredholm resolvents
Journal of Computer and System Sciences, 1968 AbstractIt is shown that the solution to every matrix Riccati equation can be generated by the resolvent of a certain Fredholm integral operator and, conversely, this resolvent can be determined from the corresponding Riccati solution. This result leads to a computational scheme, based on initial-value methods, for solving a large class of Fredholm ...
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 1997 The representation of Nevanlinna Pick Problem is well known, see [7], [8] and [11]. The aim of this paper is to find the necessary and sufficient condition for the solution of Nevanlinna Pick Problem and to show that there is a one-to-one correspondence ...
A. A. El-Sabbagh
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Quantum Scattering Theory in a Discrete Representation
EPJ Web of Conferences, 2016 The approach to solving few-body scattering problems in a discrete representation of the stationary wave packets is described briefly. By projecting into the wave-packet basis, all the operators and wave functions are represented with finite matrices and
Rubtsova O.A. +2 more
doaj +1 more source
Matrix biorthogonal polynomials on the real line: Geronimus transformations [PDF]
Bulletin of Mathematical Sciences, 2019 In this paper, Geronimus transformations for matrix orthogonal polynomials in the real line are studied. The orthogonality is understood in a broad sense, and is given in terms of a nondegenerate continuous sesquilinear form, which in turn is determined ...
Gerardo Ariznabarreta +3 more
doaj +1 more source
Compartment-Resolved Proteomics with Deep Extracellular Matrix Coverage
BIO-PROTOCOLThe extracellular matrix (ECM) is a complex network of proteins that provides structural support and biochemical cues to cells within tissues. Characterizing ECM composition is critical for understanding this tissue component's roles in development, homeostasis, and disease processes.
Maxwell McCabe +2 more
openaire +3 more sources