Results 111 to 120 of about 457,280 (245)
Resolvent operator theory of sequential quantum processes
The Mower sequential decay theory of quantum processes has been extended in order formally to remove certain spurious poles in the matrix elements of the resolvent operator, and to recast the results into a more symmetrical general form. A special choice
Dalton B.J., Cresser J.D.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
In this article, we study the asymptotical stability in p-th moment of mild solutions to a class of fractional impulsive partial neutral stochastic integro-differential equations with state-dependent delay in Hilbert spaces.
Zuomao Yan, Hongwu Zhang
doaj
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
On the level sets of the resolvent norm of a linear operator
We construct a bounded linear operator on a Banach space and a closed densely defined operator on a Hilbert space with resolvent norms that are constant in a neighbourhood of zero. We also discuss cases where the norm of the resolvent of a bounded linear
Shargorodsky, E
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Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Use Dr. W.W. Carpenter's Calculi Resolvent, for the kidneys ...
Trade card advertising Dr. W.W. Carpenter's Calculi Resolvent, a remedy prepared by the Calculi Resolvent Manufacturing Co., Cleveland, Ohio.
core
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source

