Results 31 to 40 of about 844 (219)

Approximate controllability for a stochastic elastic system with structural damping and infinite delay

open access: yesOpen Mathematics, 2023
In this article, we study the existence of mild solutions and the approximate controllability for a class of stochastic elastic systems with structural damping and infinite delay in Hilbert spaces.
Peng Jiankui   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Properties of the resolvent of singular q-Dirac operators

open access: yesElectronic Journal of Differential Equations, 2020
In this article, we investigate the resolvent operator of a singular q-Dirac system. We obtain an integral representations for the resolvent of this system, in terms of the spectral function.
Bilender P. Allahverdiev, Huseyin Tuna
doaj  

GENERALIZED RESOLVENTS OF OPERATORS GENERATED BY INTEGRAL EQUATIONS

open access: yesПроблемы анализа, 2018
We define a minimal operator L0 generated by an integral equation with an operator measure and give a description of the adjoint operator L∗0. We prove that every generalized resolvent of L0 is an integral operator and give a description of boundary ...
V. M. Bruk
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Investigation of the Spectral Properties of a Non-Self-Adjoint Elliptic Differential Operator

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2021
Non-self-adjoint operators have many applications, including quantum and heat equations. On the other hand, the study of these types of operators is more difficult than that of self-adjoint operators.
Arezoo Ghaedrahmati, Ali Sameripour
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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