Results 81 to 90 of about 457,280 (245)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Resolvent set of the M/MB/1 operator [PDF]

open access: yes, 2002
First, we prove that the M/MB/1 operator is a conservative operator, thus showing that the M/MB/1 queueing model has a unique positive time-dependent solution which satisfies the probability condition, and then prove that all points on the imaginary axis
Gupur, Geni
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, Volume 600, Issue 18, Page 2686-2694, September 2026.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Regular approximation of singular Sturm–Liouville problems with eigenparameter dependent boundary conditions

open access: yesBoundary Value Problems, 2020
In this paper we consider singular Sturm–Liouville problems with eigenparameter dependent boundary conditions and two singular endpoints. The spectrum of such problems can be approximated by those of the inherited restriction operators constructed.
Maozhu Zhang, Kun Li, Hongxiang Song
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Spectral representation of the resolvent of a discrete operator [PDF]

open access: yes, 1988
Let T be a discrete linear operator in a Hilbert space H with spectrum σ(T) = λii = 1∞, let Rλ(T) denote the resolvent of T, and let Pi denote the projection of H onto the generalized eigenspace N((γi,I − T)mj) along R((γi, I − T)mj), where mi is the ...
Lang, Patrick   +3 more
core   +1 more source

Dichotomy and H^infinity functional calculi

open access: yesElectronic Journal of Differential Equations, 1995
densely defined closed operator on a Banach space is studied. We give conditions under which an operator with an $H^infty$ functional calculus has dichotomy.
R. DeLaubenfels, Y. Latushkin
doaj  

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