Results 71 to 80 of about 519,621 (251)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Semiclassical Resonances via Meromorphy of the Resolvent and the S-Matrix

open access: yesInternational Journal of Analysis and Applications, 2020
The purpose of this paper is to describe the basic problems of resonances via meromorphic continuation of the resolvent and the scattering matrix. An example from mathematical physics is given by investigating the poles of the resolvent of semiclassical ...
Soumia Belmouhoub   +2 more
doaj  

On the bounded invertibility of a Schr¨odinger operator with a negative parameter in the space L2(Rn )

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2019
The Schrödinger operator L = -∆ + q ( x ) , x ∈ Rn, is one of the main operators of modern quantum mechanics and theoretical physics. It is known that many fundamental results have been obtained for the Schrödinger operator L .
M.B. Muratbekov, M.M. Muratbekov
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Dichotomy and H^infinity functional calculi

open access: yesElectronic Journal of Differential Equations, 1995
densely defined closed operator on a Banach space is studied. We give conditions under which an operator with an $H^infty$ functional calculus has dichotomy.
R. DeLaubenfels, Y. Latushkin
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Existence of the Mild Solutions for Delay Fractional Integrodifferential Equations with Almost Sectorial Operators

open access: yesAbstract and Applied Analysis, 2012
This paper is concerned with the existence of mild solutions for the fractional integrodifferential equations with finite delay and almost sectorial operators in a separable Banach space X.
Fang Li
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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