Results 71 to 80 of about 870 (267)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Further Research on the M/G/1 Retrial Queueing Model with Server Breakdowns
We study spectral properties of the operator which corresponds to the M/G/1 retrial queueing model with server breakdowns and obtain that all points on the imaginary axis except zero belong to the resolvent set of the operator and 0 is not an eigenvalue ...
Ehmet Kasim, Geni Gupur
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Bregman Distance and Strong Convergence of Proximal-Type Algorithms
The purpose of this paper is to discuss some fundamental properties of Bregman distance, generalized projection operators, firmly nonexpansive mappings, and resolvent operators of set-valued monotone operators corresponding to a functional Φ(∥·∥).
Li-Wei Kuo, D. R. Sahu
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Error-correcting codes from k-resolving sets
13 pages, 2 ...
Robert Bailey, Ismael González Yero
openaire +4 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
More large sets of resolvable MTS and resolvable DTS with odd orders
Consider a Mendelsohn (resp. directed) triple system on a set \(X\) of order \(v\). Such a triple system is called resolvable if its blocks can be partitioned into subsets (called parallel classes), each containing every element of \(X\) exactly once. A large set \(L\) of Mendelsohn (resp.
Qingde Kang, Hongtao Zhao
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

