Results 91 to 100 of about 147,496 (294)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Total resolving number of edge cycle graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2020
Let be a simple connected graph. An ordered subset W of V is said to be a resolving set of G if every vertex is uniquely determined by its vector of distances to the vertices in W. The minimum cardinality of a resolving set is called the resolving number
J. Paulraj Joseph, N. Shunmugapriya
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Resolving Predictive Multiplicity for the Rashomon Set

open access: yesProceedings of the AAAI Conference on Artificial Intelligence
The existence of multiple, equally accurate models for a given predictive task leads to predictive multiplicity, where a ``Rashomon set'' of models achieve similar accuracy but diverge in their individual predictions. This inconsistency undermines trust in high-stakes applications where we want consistent predictions.
Parian Haghighat   +2 more
openaire   +2 more sources

On the Families of Graphs With Unbounded Metric Dimension

open access: yesIEEE Access, 2019
A family G of connected graphs is a family with unbounded metric dimension if dim(G) is not constant and depends on the order of graph. In this paper, we compute the metric dimension of the splitting graphs S(Pn) and S(Cn) of a path and cycle.
Heng Pan   +4 more
doaj   +1 more source

The Strong Resolving Graph and the Strong Metric Dimension of Cactus Graphs

open access: yesMathematics, 2020
A vertex w of a connected graph G strongly resolves two distinct vertices u,v∈V(G), if there is a shortest u,w path containing v, or a shortest v,w path containing u. A set S of vertices of G is a strong resolving set for G if every two distinct vertices
Dorota Kuziak
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Minimal doubly resolving sets and the strong metric dimension of Hamming graphs [PDF]

open access: yes, 2012
We consider the problem of determining the cardinality ?(H2,k) of minimal doubly resolving sets of Hamming graphs H2,k. We prove that for k ? 6 every minimal resolving set of H2,k is also a doubly resolving set, and, consequently, ?(H2,k) is ...
Jozef Kratica   +7 more
core   +1 more source

Metric dimension of star fan graph

open access: yesScientific Reports
Every node in a network is said to be resolved if it can be uniquely identified by a vector of distances to a specific set of nodes. The metric dimension is equivalent to the least possible cardinal number of a resolving set.
S. Prabhu   +2 more
doaj   +1 more source

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