Results 61 to 70 of about 60,505 (275)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On the metric dimension of bipartite graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2023
For an ordered subset [Formula: see text] of vertices and a vertex v in a connected graph G, the ordered k-vector [Formula: see text] is called the representation of v with respect to W, where [Formula: see text] is the distance between v and wi, for ...
M. Anandha Jothi, K. Sankar
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

On the Metric Dimension of Generalized Petersen Multigraphs

open access: yesIEEE Access, 2018
In this paper, we study the metric dimension of barycentric subdivision of Möbius ladders and the metric dimension of generalized Petersen multigraphs. We prove that the generalized Petersen multigraphs denoted by $P(2n,n)$ have metric dimension
Muhammad Imran   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Computation of the Double Metric Dimension in Convex Polytopes

open access: yesJournal of Mathematics, 2021
A source detection problem in complex networks has been studied widely. Source localization has much importance in order to model many real-world phenomena, for instance, spreading of a virus in a computer network, epidemics in human beings, and rumor ...
Liying Pan   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Q-Rung Probabilistic Dual Hesitant Fuzzy Sets and Their Application in Multi-Attribute Decision-Making

open access: yes, 2020
The probabilistic dual hesitant fuzzy sets (PDHFSs), which are able to consider multiple membership and non-membership degrees as well as their probabilistic information, provide decision experts a flexible manner to evaluate attribute values in ...
Jun Wang, Hegong Lei, Li Li
core   +1 more source

Partition Dimension of Generalized Petersen Graph

open access: yesComplexity, 2021
Let G=VG,EG be the connected graph. For any vertex i∈VG and a subset B⊆VG, the distance between i and B is di;B=mindi,j|j∈B. The ordered k-partition of VG is Π=B1,B2,…,Bk. The representation of vertex i with respect to Π is the k-vector, that is, ri|Π=di,
Hassan Raza   +3 more
doaj   +1 more source

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