Results 51 to 60 of about 50,563 (299)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Bidirectional multiple port dc/dc transformer based on a series resonant converter [PDF]
, 2013 In this paper a novel bidirectional multiple port dc/dc transformer topology is presented. The novel concept for dc/dc transformer is based on the Series Resonant Converter (SRC)topology operated at its resonant frequency point.
Alou Cervera, Pedro +4 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Energies, 2022 A full-bridge diode-clamped multilevel LLC resonant converter suitable for power conversion systems that use high input voltage, such as railway vehicles, is proposed in this paper. In order to eliminate the voltage deviations of the capacitors connected
Min-Sup Song, Jae-Bum Lee
doaj +1 more source
A review on flicker-free ac-dc LED drivers for single-phase and three-phase ac power grids [PDF]
, 2019 Light-Emitting Diodes (LEDs) are coming strongly into the lighting market due to their advantages over conventional lighting solutions: energy efficient, controllable in both light and color, long lifetime, lack of a warm-up period and high power density.
Arias Pérez de Azpeitia, Manuel +5 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
IEEE Access, 2020 This paper presents and analyzes an AC-DC power converter structure, which is comprised of a Power Factor Correction (PFC) module and a LLC resonant DC-DC converter module.
Guidong Zhang +6 more
doaj +1 more source
Voltage regulation considerations for the design of hybrid distribution transformers [PDF]
, 2014 The future substation depends on finding a way to mitigate the effects of the drawbacks of the conventional legacy by employing the efficiency of the solid state switches [1].
Alqarni, M, Darwish, M, Radi, MA
core +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source