Results 51 to 60 of about 50,703 (300)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Comparison of single-phase matrix converter and H-bridge converter for radio frequency induction heating [PDF]

, 2007
This paper compares the newly developed single-phase matrix converter and the more conventional H- bridge converter for radio frequency induction heating.
Bingham, Chris, Foster, M. P., Nguyen-Quang, N., Stone, D. A.   +3 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Design Methodology of Tightly Regulated Dual-Output LLC Resonant Converter Using PFM-APWM Hybrid Control Method [PDF]

, 2019
A dual-output LLC resonant converter using pulse frequency modulation (PFM) and asymmetrical pulse width modulation (APWM) can achieve tight output voltage regulation, high power density, and high cost-effectiveness.
HakSun Kim, HwaPyeong Park, JeeHoon Jung, Ji, Mina Kim, Xi   +5 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Pulse-Amplitude-Modulation Full-Bridge Diode-Clamped Multilevel LLC Resonant Converter Using Multi-Neighboring Reference Vector Discontinuous PWM

Energies, 2022
A full-bridge diode-clamped multilevel LLC resonant converter suitable for power conversion systems that use high input voltage, such as railway vehicles, is proposed in this paper. In order to eliminate the voltage deviations of the capacitors connected
Min-Sup Song, Jae-Bum Lee
doaj   +1 more source

Design and implementation of magnetron power supply and emulator [PDF]

, 2016
The paper presents a novel resonant based high performance power converter solution for industrial magnetron systems. Based the characteristics of the magnetron, an emulator prototype is also proposed to represent the magnetron load behaviour in a ...
Abodhir, Nourdeen, Clare, Jon C., Ji, Chao, Watson, Alan James   +3 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Hybrid Resonant Converter with Three Half-Bridge Legs for Wide Voltage Operation

Applied Sciences, 2019
This paper studied a hybrid resonant converter with three half bridge legs for wide input voltage operation. Compared to the conventional resonant converters with narrow voltage operation, the presented converter can achieve wider voltage operation.
Bor-Ren Lin, Yong-Sheng Zhuang
doaj   +1 more source