Results 61 to 70 of about 56,208 (298)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Nonlinear modeling of ELM mitigation with RMP on HL-2A

Nuclear Fusion
Nonlinear modeling of mitigation of the edge localized mode (ELM) with resonant magnetic perturbation (RMP) is performed for the HL-2A tokamak, utilizing the three-dimensional (3D) magnetohydrodynamic code JOREK.
L. Wang, G.Z. Hao, M. Becoulet, Y.Q. Liu, Y.H. Xu, J.Q. Li, P.F. Zheng, D. Hu, S.L. Hu, G.Q. Dong, S. Wang, X.X. He, T.F. Sun, G.T.A. Huijsmans, W.L. Zhong, the JOREK Team   +15 more
doaj   +1 more source

Transport and acceleration mechanism of fast ions during edge localized modes in ASDEX Upgrade

Nuclear Fusion, 2023
Observations of enhanced fast-ion losses during edge localized modes (ELMs) have been reported in the ASDEX Upgrade tokamak, revealing losses above the injection energy. This suggests that fast ions can be accelerated and lost due to the ELMs.
J.F. Rivero-Rodríguez, J. Galdon-Quiroga, J. Domínguez-Palacios, M. García-Muñoz, D. Garcia-Vallejo, J. Gonzalez-Martin, K.G. McClements, L. Sanchís, K. Särkimäki, A. Snicker, Y. Todo, L. Velarde, E. Viezzer, the ASDEX Upgrade Team   +13 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Resonant Absorption and Fluctuations via Hybrid Simulations on Coronal Loops. I. Plasma Multifluid Description

The Astrophysical Journal
We investigate the resonant absorption process of a combination of left- and right-hand polarized waves (with a fixed perturbation amplitude) in a plasma slab with linearly inhomogeneous particle densities.
Hugo A. Carril, Jaume Terradas, Roberto E. Navarro, Adolfo F. Viñas, Marcel Goossens   +4 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Metrics and extrapolation of resonant magnetic perturbation thresholds for ELM suppression

Nuclear Fusion
This large database study of resonant magnetic perturbation (RMP) edge localized mode (ELM) suppression thresholds in the AUG, DIII-D, EAST, and KSTAR tokamaks details the key strengths and weaknesses of RMP metrics. The RMP ELM suppression database used
N.C. Logan, S.K. Kim, S.M. Yang, J.-K. Park, Q. Hu, N. Leuthold, C. Paz-Soldan, S. Gu, D. Weisberg, H. Wang, Y. Sun, P. Xie, G. Nina Montano, T. Wang, M.W. Kim, M. Willensdorfer, EUROfusion WPTE Team, the ASDEX Upgrade Team   +17 more
doaj   +1 more source

Resonant Dynamics of Strongly Interacting SU(n) Fermionic Atoms in a Synthetic Flux Ladder

PRX Quantum, 2022
We theoretically study the dynamics of n-level spin-orbit coupled alkaline-earth fermionic atoms with SU(n) symmetric interactions. We consider three-dimensional lattices with tunneling along one dimension, and the internal levels treated as a synthetic ...
Mikhail Mamaev, Thomas Bilitewski, Bhuvanesh Sundar, Ana Maria Rey   +3 more
doaj   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Effect of resonant magnetic perturbation on edge–core turbulence spreading in a tokamak plasma

Nuclear Fusion
Turbulence spreading from the edge to the core region of a tokamak with a resonant magnetic perturbation (RMP) is investigated using an electromagnetic Landau-fluid model in a toroidal geometry.
Guangzhi Ren, Lai Wei, Jiquan Li, Zheng-Xiong Wang   +3 more
doaj   +1 more source