Results 61 to 70 of about 106,916 (291)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Performance of a Modified Negative Branch Unstable Resonator [PDF]
Far field deployment of high power chemical oxygen iodine laser (COIL) affords optimally adapted resonator architectures. Such resonators shall enable high brightness operation.
Grünewald, Karin +4 more
core
Tunable fractional-order photonic differentiator based on the inverse Raman scattering in a silicon microring resonator [PDF]
A novel photonic fractional-order temporal differentiator is proposed based on the inverse Raman scattering (IRS) in the side-coupled silicon microring resonator.
Yu, Chongxiu +9 more
core +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Cylindrical resonator filled with four alternating sectors of DPS and DNG materials [PDF]
A circular cylindrical metallic resonator with four alternating sectors of DPS and DNG materials is analyzed, in the frequency domain. The two materials are linear, lossless, homogeneous, and anti-isorefractive to each other.
Graglia, Roberto +7 more
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Tunable ring resonator filter for OFDM Transmission systems [PDF]
A novel tunable filter is theoretically demonstrated. It is based on a ring resonator with an amplifier and a noise filter in the loop. This optoelectronic device has potential as a high-sensitivity receiver and as a tunable demultiplexer in OFDM ...
López Amo, Manuel +8 more
core +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source

