Results 291 to 300 of about 420,810 (383)

Virulence‐Selective Trap–Capture–Kill Antibacterial Nanostructures With Immune–Metabolic Regulation for Treating Implant‐Associated Infections

Advanced Science, EarlyView.
A virulence‐selective antibacterial system based on fascaplysin derivative 14‐modified TiO2 nanostructure (F‐14‐TNA) is developed for treating implant‐associated infections. F‐14‐TNA selectively traps hyperpathogenic bacteria via chemotaxis, captures them electrostatically, and kills them via reactive oxygen species‐mediated pathways.
Xiaodong Hu, Jiaqi Zhong, Yujiong Chen, Botao Liu, Tianyu Du, Weilai Zhu, Minzhe Zheng, Hongze Liang, Jiahua Ni, Zhaoxiang Peng   +9 more
wiley   +1 more source

Bone Microstructural Deterioration and miR-155/<i>RHOA</i>-Mediated Osteoclastogenesis in Type 2 Diabetes Mellitus. [PDF]

Int J Mol Sci
Alaleeli MM, Kaimala S, Adeghate E, Mohsin S.   +3 more
europepmc   +1 more source

Tailored Electro–Magnetic–Porous Multigradient Nanoarchitectonics for Absorption‐Dominated Electromagnetic Interference Shielding and Adaptive Multifunctionality

Advanced Science, EarlyView.
An electro–magnetic–porous multigradient nanofibrous electromagnetic interference (EMI) membrane is fabricated via shear‐induced in situ fibrillation and layer‐by‐layer assembly. Leveraging a multigradient‐induced “impedance matching–polarization–reabsorption” synergistic mechanism, the membrane achieves absorption‐dominated high‐efficiency EMI ...
Runze Shao, Guilong Wang, Wenyu Wang, Jialong Chai, Guoqun Zhao, Guizhen Wang   +5 more
wiley   +1 more source

A mathematical model of metacarpal subchondral bone adaptation, microdamage and repair in racehorses. [PDF]

J R Soc Interface
Pan M, Malekipour F, Pivonka P, Morrice-West AV, Flegg JA, Whitton RC, Hitchens PL.   +6 more
europepmc   +1 more source

PDZK1 Protects Against RPE Senescence by Targeting the 14‐3‐3ε‐mTOR Axis to Attenuate Early Diabetic Retinopathy

Advanced Science, EarlyView.
PDZK1 down‐regulation couples high‐glucose stress to RPE senescence via a PDZK1–14‐3‐3ε–mTOR axis. Restoring PDZK1 or clearing senescent cells rescues retinal homeostasis and mitigates early diabetic retinopathy (DR). This study provides direct evidence linking RPE cell senescence to DR pathogenesis and reveals a promising therapeutic strategy for DR ...
Jian Zhao, Junbiao Zhang, Yanli Liu, Lili Wang, Chunxi Huang, Wei Chi, Meixia An   +6 more
wiley   +1 more source

Transcriptomics Guided Engineering of Exosome‐Encapsulated Bifunctional Nanosheets Targeting the Immune‐PI3K/Akt Axis for Osteoporosis Therapy

Advanced Science, EarlyView.
A multifunctional nanosheet–exosome hybrid system incorporating f‐CA(OH) nanosheets enriched with abundant surface vacancies are developed. These nanosheets fuse with natural exosomes, endowing them with nanozyme‐like catalytic capabilities while retaining their inherent biological functions.
Rongze Tang, Guanhong Liu, Congcong Wang, Minghao Chao, Guangyu Ma, Pengjin Wei, Siling Du, Junjie Li, Yufan Liu, Chaonan Jing, Guoquan Wu, Ming Guan, Hongliang Chen, Fenglei Gao   +13 more
wiley   +1 more source

Thermal Behaviour of Teeth With Internal Root Resorption During Obturation and Enhancing Thermal Simulations: A Finite-Element Analysis. [PDF]

Int Dent J
Kabakci A, Yilmaz A, Helvacioglu-Yigit D, Nawar NN, Kim HC.   +4 more
europepmc   +1 more source

Innovative Photon‐Engineered Fluorescent Tri‐Layer Polymeric Coatings for Sub‐Ambient Colored Radiative Cooling

Advanced Science, EarlyView.
This work provides a photoluminescence‐enhanced coating material solution for enhancing solar reflectance and coloration, systematically investigating the fluorescence’s role on the optical performance. All colored coatings exhibit excellent sub‐ambient cooling capacity (historically high solar reflectance and over 0.96 infrared emittance), while ...
Tao Wang, Ying Liu, Qingdong Xuan, Xue Ma, Yanbo Fang, You Dong, Dangyuan Lei, Jian‐Guo Dai   +7 more
wiley   +1 more source

Leaf Nutrient Resorption Efficiency Aligns with the Leaf but Not Root Economic Spectrum in a Tropical Mangrove Forest. [PDF]

Plants (Basel)
Jiang D, Nie T, He Q, Xu Z, Chen HYH, Feng E, Peñuelas J.   +6 more
europepmc   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

Advanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu, Jintao Song, Mengjiao Guo, RuZe Ma, Mingyang Du, Zhe Xun, Xu Liu, RongXia Xu, Xiaochun Xie, Peilin Qi, Yujie Chen, Dan Shao, Chao Yang, Liang Wang, Xiaoyu Song, Difei Wang   +15 more
wiley   +1 more source