Results 91 to 100 of about 40,368,284 (333)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Making Sense of the Resource-Based View? [PDF]
, 2007 The Resource Based View (RBV) of strategic management has been criticized for relying\ud on inconsistent assumptions of rationality, and mutually inconsistent underlying\ud hypotheses.
Tywoniak, Stephane
core +1 more source
International Journal of Management and Economics, 2015 The dynamic capabilities view posits that a firm’s success is largely driven by its ability to adapt to a changing environment to secure value creating potential and, thus achieve a competitive advantage.
Wójcik Piotr
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Towards a Dynamic Resource-Based View Insights from Austrian Capital and Entrepreneurship Theory [PDF]
Over the last two decades the resource-based view (“RBV”) has become dominant in the strategic management field. It has often been observed that the RBV is lacking in the dynamic dimension.
Nicolai J. Foss, Ibuki Ishikawa
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Theoretical foundation of the EFQM model: the resource-based view [PDF]
, 2005 This paper analyses in detail the European quality model and proves that it uses, as implicit theoretical basis, a brand-new organizational theory, i.e. the resource-based view.
Rubén Fernández-Ortiz +3 more
core +1 more source
Composition-based view of the firm as a promising approach to studying small businesses
Production, 2019 Paper aims Extant Literature based on the resource-based view (RBV) of the firm suggests that it can be used to study organizations of all types and sizes.
Shehnaz Tehseen +5 more
doaj +1 more source