Results 71 to 80 of about 40,368,284 (333)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Organizational capabilities as a source of competitive advantage: a conceptual framework

open access: yesAgricultural Economics (AGRICECON), 2010
Organizational capabilities are recognized in the resource-based view strategy literature as one of the primary source of competitive advantage. This article reviews models to analyse organizational capabilities to provide framework for wider adoption of
Ivana TICHÁ
doaj   +1 more source

Leveraging Digital Resources: A Resource-Based View Perspective

open access: yesGolden Ratio of Human Resource Management
In today's rapidly evolving digital landscape, organisations are challenged to strategically deploy digital resources to secure competitive advantage. Drawing upon the Resource-Based View (RBV) theory, this paper explores the intricate interplay between ...
M. Willie
semanticscholar   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Resource allocation in communication networks using market-based agents

open access: yes, 2004
This work describes a system that allocates end-to-end bandwidth, in a switched meshed communications network. The solution makes use of market-based software agents that compete in a number of decentralised marketplaces to buy and sell bandwidth ...
Haque, N.   +13 more
core   +1 more source

La orientacion emprendedora a nivel de la firma.

open access: yesMultidisciplinary Business Review, 2008
El crecimiento económico de los países pasa por incentivar y desarrollar la creación de nuevas empresas, las que deben poseer ciertas capacidades para un mejor desempeño y generar ventajas competitivas.
M. Soledad Etchebarne L.   +2 more
doaj  

Reconciling Resource-Based View and Competency-Based View of Start-Up Formation in Universities

open access: yesIEEE Access, 2020
Given the industrial and economic importance of start-up formation in universities, researchers have adopted a variety of theoretical approaches, including embeddedness theory, ecosystem theory, resource-based view (RBV), and competency-based view (CBV).
Kyoung-Joo Lee, Yang-Joong Yun
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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