Results 71 to 80 of about 2,581,993 (306)

What you get is what you need? The role of venture capitalists in managing growth of new ventures [PDF]

open access: yes
The resource-based view is suggested as a useful concept to shed light on the particular challenges of high potential companies on their way to building a thriving and growing company.
Achleitner, Ann-Kristin   +1 more
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Determinant factors in adopting socio-environmental certifications in coffee farms¹

open access: yesRevista de Economia e Sociologia Rural, 2014
Certified coffee production is an opportunity for the grower to differ his product. However, the number of certified producers is still relatively small.
Eduardo Cesar Silva   +3 more
doaj  

Addressing the Resource-Based View: Determinants That Drive Chinese Universities to Offer MOOCs

open access: yesInternational Review of Research in Open and Distributed Learning
This study involved 51 Chinese universities from the Quacquarelli Symonds (QS) World University Ranking 2021. With based the resource-based view (RBV) as a framework, it aimed to identify the determinants of human resource capital that were related to ...
Kai Wang   +2 more
doaj   +1 more source

MODERN AREAS OF DEVELOPMENT OF RESOURCE-BASED THEORY

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2015
The essence of resource-based view is focus on using unique and rare combination of resources, core competences and organizational capabilities of the firm.
O. Miroshnychenko, K. Kryvko
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Family Entrepreneurship Orientation in Family Owned SMEs: A Key Resource for Internationalization?

open access: yesEntrepreneurial Business and Economics Review, 2018
A B S T R A C T Objective: The main goal of this article is to find the answer to the questions: what is the nature of the internationalization of family businesses from Poland?
Alicja Hadryś-Nowak
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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