Results 61 to 70 of about 2,704,412 (312)
Frontiers in WaterGroundwater is a crucial resource for global populations and economies, particularly in developing countries where water scarcity is a growing concern.
Estella Mgala +3 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cost-effectiveness of portable-automated ABR for universal neonatal hearing screening in India
Frontiers in Public HealthThe World Health Organization considers Universal Neonatal Hearing Screening (UNHS) essential to global public health. Rashtriya Bal Swasthya Karyakram has included newborn hearing screening in India since 2013.
Krushna Chandra Sahoo +8 more
doaj +1 more source
Combined Floating Offshore Wind and Solar PV
Journal of Marine Science and Engineering, 2020 To mitigate the effects of wind variability on power output, hybrid systems that combine offshore wind with other renewables are a promising option. In this work we explore the potential of combining offshore wind and solar power through a case study in ...
Mario López +2 more
doaj +1 more source
Library resources, student success and the distance-learning university [PDF]
, 2018 Purpose - Research at the Open University Library Services has been investigating the relationshipbetween access to online library resources and student success to help to understand whether there is asimilar relationship at a distance-learning ...
Baker, Kirsty +2 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Lunar Resource Assessment: an Industry Perspective [PDF]
The goals of the U.S. space program are to return to the Moon, establish a base, and continue onward to Mars. To accomplish this in a relatively short time frame and to avoid the high costs of transporting materials from the Earth, resources on the Moon ...
Altenberg, B. H. +2 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Human resources impact assessment.
Bulletin of the World Health Organization, 2003 Has been published before in: Bull.
Van Lerberghe, W. +2 more
openaire +3 more sources
Where the wild things are: Examining the intersection between the RMA 1991 and the Wildlife Act 1953 [PDF]
, 2009 Recent case law has drawn attention to the impact of the Wildlife Act 1953 (WA) and its intersection with the Resource Management Act 1991 (RMA). Some of the decisions have been summarised in previous RMLA publications and it is the intention of this ...
Wallace, Philippa Jane
core +1 more source