Results 81 to 90 of about 135,773 (264)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
, 1993 This is an OTA resource analysis ...
United States. Congress. Office of Technology Assessment.
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Social assessment : theory, process and techniques [PDF]
, 1990 Impetus in New Zealand for the development of theory, process, and techniques of social assessment comes from major social change. This change has been in the restructuring and reform of the public service and the resource economy. It has been paralleled
Goodrich, Colin. G. +2 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Zircon U-Pb Geochronology and Uranium-Production Capacity of the Taoshan Complex in Southern Jiangxi
Yankuang ceshi, 2014 The Taoshan granite complex located at the North-East part of the Nanling region, hosts the largest granite-related uranuim ore field in China. Baohuashan granite and Huangpi granite are two major components of the Taoshan granite complex.
Tian zejin +6 more
doaj +2 more sources
International Journal of Forestry Research, 2015 Power relation among stakeholders is a key concept in collaborative approaches. This study aims to examine the reality of the acclaimed power sharing in Participatory Forest Management (PFM) and implication of existing power relation to the national ...
Angelingis Akwilini Makatta +2 more
doaj +1 more source
Solar radiation resource assessment [PDF]
, 1990 The bulletin discusses the following: introduction; Why is solar radiation resource assessment important Understanding the basics; the solar radiation resource assessment project; and future ...
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