Results 91 to 100 of about 135,773 (264)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Health-related quality of life among multimorbid patients using the EQ-5D-5L value set for India

Frontiers in Public Health
Multimorbidity presents major challenges to healthcare systems worldwide. Assessing health-related quality-of-life (HRQoL) in multimorbid patients is essential for understanding the overall impact of the patient’s health conditions on wellbeing and the ...
Krushna Chandra Sahoo, Abhinav Sinha, Girish Chandra Dash, Rakesh Kumar Sahoo, Debdutta Bhattacharya, Purna Chandra Dash, Lalatendu Mohanty, Pranab Mahapatra, Kavitha Rajsekhar, Sanghamitra Pati   +9 more
doaj   +1 more source

IEA Wind Task 32: Wind Lidar Identifying and Mitigating Barriers to the Adoption of Wind Lidar

Remote Sensing, 2018
IEA Wind Task 32 exists to identify and mitigate barriers to the adoption of lidar for wind energy applications. It leverages ongoing international research and development activities in academia and industry to investigate site assessment, power ...
Andrew Clifton, Peter Clive, Julia Gottschall, David Schlipf, Eric Simley, Luke Simmons, Detlef Stein, Davide Trabucchi, Nikola Vasiljevic, Ines Würth   +9 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

HART - Federal Housing Needs Assessment Template Database - Canada, all provinces and territories, at the Census Subdivision (CSD), Census Division (CD), and Census Metropolitan Area/Census Agglomeration (CMA/CA) level [PDF]

Note: April 22, 2025: Updates to "CHN by income and HH size_v3". --------------------------------------------------------------------------------------------------------------------------------- Note: April 16, 2025: Updates to the following files ...
Housing Assessment Resource Tools
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Estimation of the Motion-Induced Horizontal-Wind-Speed Standard Deviation in an Offshore Doppler Lidar

Remote Sensing, 2018
This work presents a new methodology to estimate the motion-induced standard deviation and related turbulence intensity on the retrieved horizontal wind speed by means of the velocity-azimuth-display algorithm applied to the conical scanning pattern of a
Miguel A. Gutiérrez-Antuñano, Jordi Tiana-Alsina, Andreu Salcedo, Francesc Rocadenbosch   +3 more
doaj   +1 more source

Resource management : Issues, visions, practice | Kā taoka mana whakahaere : He take, he moemoeā, he mahi whakahaere : A symposium, Friday 5 - Monday 8 July 1996 : Proceedings [PDF]

, 1996
Shared experiences : the basis for a cooperative approach to identifying and implementing more sustainable land management practices / Willy Allen and Ockie Bosch -- Cites : an effective method for addressing the causes of the trade / Peter Anderson ...
Centre for Resource Management
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

PacWave cotemporal resource assessment of waves, winds, and currents [PDF]

The Pacific Northwest of the United States is characterized by one of the greatest annual mean wave power resources in the world. As a result, the wave energy resource offshore of Oregon has been characterized, based on physical buoy data and hindcast ...
Lou, Junhui, Robertson, Bryson
core