Results 111 to 120 of about 1,523,539 (313)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Deliverable DJRA1.2. Solutions and protocols proposal for the network control, management and monitoring in a virtualized network context [PDF]

open access: yes, 2009
This deliverable presents several research proposals for the FEDERICA network, in different subjects, such as monitoring, routing, signalling, resource discovery, and isolation. For each topic one or more possible solutions are elaborated, explaining the
Cervelló Pastor, Cristina   +3 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Indochinese bamboos: biodiversity informatics to assist the identification of “vernacular taxa” [PDF]

open access: yes, 2010
Bamboo (Bambusoides – Gramineae) is one of the most important natural resource in Southeast Asia. However, bamboo identification has many difficulties.
Bich Loan Nguyen, Thi   +3 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Design of metadata elements for digital news articles in the omnipaper project [PDF]

open access: yes, 2003
This paper examines and proposes a set of metadata elements for describing digital news articles for the benefit of distributed and heterogeneous news resource discovery.
Baptista, Ana Alice   +2 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Metadata elements for digital news resource description [PDF]

open access: yes, 2003
This paper examines and proposes a set of metadata elements for describing digital news articles for the benefit of distributed and heterogeneous news resource discovery.
Baptista, Ana Alice   +2 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

FOSTER D2.1 - Technical protocol for rich metadata categorization and content classification [PDF]

open access: yes, 2014
FOSTER aims to set in place sustainable mechanisms for EU researchers to FOSTER OPEN SCIENCE in their daily workflow, supporting researchers optimizing their research visibility and impact and the adoption of EU open access policies in line with the EU ...
Davidson, Joy   +4 more
core  

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