Results 51 to 60 of about 232,317 (248)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Connecting RDA and RDF: Linked Data for a Wide World of Connected Possibilities
Pennsylvania Libraries: Research & Practice, 2015 Libraries have struggled with connecting a plethora of content and the metadata stored in catalogs to patrons. Adding more value to catalogs, more tools for reference librarians, and enriched patron search, linked data is a means to connect more people ...
Ashleigh Faith, Michelle Chrzanowski
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
JLIS.it, 2018 After a methodological introduction and a recap of the evolutionary steps of the two descriptive models, the article aims at underlining contact points and differences between the Resource Description and Access (RDA) guidelines and the conceptual model ...
Giorgia Di Marcantonio
doaj +6 more sources
Sacherschließung unter FRBR und RDA in Theorie und Praxis
o-bib. Das offene Bibliotheksjournal, 2016 Zusammenfassung: Der Beitrag untersucht die Rolle der Sacherschließung in den "Functional Requirements for Bibliographic Records" (FRBR) und den damit verwandten Modellen (FRAD, FRSAD, FRBR-LRM) sowie im neuen Katalogisierungsstandard "Resource ...
Heidrun Wiesenmüller
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
An IoT Unified Access Platform for Heterogeneity Sensing Devices Based on Edge Computing
IEEE Access, 2019 With the rapid development of the Internet of Things (IoT), a large number of heterogeneous sensing devices are accessed in their proprietary ways to IoT applications, formed “silos” application mode. The growth of IoT applications has been
Lina Lan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source