Results 71 to 80 of about 1,473,023 (294)

Resource selection and data fusion for multimedia international digital libraries: an overview of the MIND project [PDF]

open access: yes, 2002
The inspiration for MIND grew out of the problems which users face when they have remote access to thousands of heterogeneous and distributed multimedia digital libraries. A user must know where to search, how to query different media, and how to combine
Gibb, F.
core  

On the Benefit of Information Centric Networks for Traffic Engineering

open access: yes, 2013
Current Internet performs traffic engineering (TE) by estimating traffic matrices on a regular schedule, and allocating flows based upon weights computed from these matrices.
Su, Kai, Westphal, Cedric
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

El objeto de la catalogación en el marco de las FRBR y el nuevo código de catalogación [PDF]

open access: yes, 2009
The changes introduced by technology in cataloging are analysed. In this new context the definition of a new cataloging code was necessary. The new code entitles Resource Description and Access (RDA) is based on FRBR model.
Picco, Paola
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

RDA for Who?

open access: yes, 2006
Article concerning the flawed development process for Resource Description and Access (RDA)
Hillmann, Diane I.
core  

Repositorios de Información como recurso de comunicación académica de Universidades Nacionales Argentinas [PDF]

open access: yes, 2013
Universities today are in a continuous process of change caused by the information society and by the knowledge society. In both cases, the cross-cutting priority is The Information and Communication Technology (TIC), introduced to broaden access to ...
del Prado, Ana Maria   +2 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Adaptive query-based sampling of distributed collections [PDF]

open access: yes, 2006
As part of a Distributed Information Retrieval system a de-scription of each remote information resource, archive or repository is usually stored centrally in order to facilitate resource selection.
C. Zhai   +10 more
core   +4 more sources

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