Results 91 to 100 of about 13,847,950 (355)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
OmniMon: Re-architecting Network Telemetry with Resource Efficiency and Full Accuracy
Conference on Applications, Technologies, Architectures, and Protocols for Computer Communication, 2020 Network telemetry is essential for administrators to monitor massive data traffic in a network-wide manner. Existing telemetry solutions often face the dilemma between resource efficiency (i.e., low CPU, memory, and bandwidth overhead) and full accuracy (
Qun Huang +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Shuiwen dizhi gongcheng dizhiThe hydrological circulation driven by tidal pumping has potentially important impacts on geochemical cycling within shallow mangrove aquifers. However, the nitrogen cycling mechanisms modulated by tidal pumping, as well as the nitrogen utilization ...
Kai YU +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Report of the Energy Efficiency Board. 2013.
, 2014 Annual; Began with 2010; ceased with 2011.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core +1 more source
On the Concept of Resource-Efficiency in NLP.
, 2023 QC 20241023Shared first ...
Dürlich, Luise +2 more
openaire +5 more sources
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
On the Efficient Extraction of Entangled Resources
IEEE Transactions on CommunicationsIn the Quantum Internet, multipartite entanglement enables a rich and dynamic overlay topology, referred to as artificial topology, upon the physical one, that can be exploited for communication purposes. In fact, the ability to extract $n$-qubits GHZ states and EPR pairs from the original multipartite entangled state constitutes the resource ...
Chen, Si-Yi +2 more
openaire +5 more sources