Results 111 to 120 of about 13,847,950 (355)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Applying Circular Thermoeconomics for Sustainable Metal Recovery in PCB Recycling

Energies
The momentum of the Fourth Industrial Revolution is driving increased demand for certain specific metals. These include copper, silver, gold, and platinum group metals (PGMs), which have important applications in renewable energies, green hydrogen, and ...
Jorge Torrubia, César Torres, Alicia Valero, Antonio Valero, Ashak Mahmud Parvez, Mohsin Sajjad, Felipe García Paz   +6 more
doaj   +1 more source

Resource use efficiency of US electricity generating plants during the SO2 trading regime: A distance function approach. [PDF]

This paper measures resource use efficiency of electricity generating plants in the United States under the SO2 trading regime. Resource use efficiency is defined as the product of technical efficiency and environmental efficiency, where the latter is ...
Kumar, Surender, Gupta, Sreekant
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Value-addition of water hyacinth and para grass through pyrolysis and hydrothermal liquefaction

Carbon Resources Conversion, 2019
Hydrothermal liquefaction (HTL) and pyrolysis (Py) of Loktak lake biomass mixture of water hyacinth (WH) and para grass (PG) were carried out at 260–300 °C and 300–500 °C to compare the products yield and chemical characteristics of the products. In case
Dinabandhu Sahoo, Ayushi Awasthi, Vaibhav Dhyani, Bijoy Biswas, Jitendra Kumar, Yenumala Sudhakara Reddy, V.P. Adarsh, Anoop Puthiyamadam, Kiran Kumar Mallapureddy, Rajeev K. Sukumaran, Sabeela Beevi Ummalyma, Thallada Bhaskar   +11 more
doaj   +1 more source

Energy Efficiency Resource Standards: Economics and Policy [PDF]

Twenty states in the United States have adopted energy efficiency resource standards (EERS) that specify absolute or per¬centage reductions in energy use relative to business as usual.
Palmer, Karen, Brennan, Timothy J.
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Characterising the high spatial heterogeneity of urban flood resilience under extreme rainfall using mobile signal data

Geomatics, Natural Hazards & Risk
Characterisation of the spatial heterogeneity of urban flood resilience (UFR) under extreme rainfall events can support decision-making in urban planning and emergency management.
Junqi Mao, Xiaoyan Cao, Runqiao Zhang, Junqing Tang, Pengjun Zhao, Huapeng Qin   +5 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source