An exact procedure for the resource-constrained weighted earliness-tardiness project scheduling problem. [PDF]
In this paper we study the resource-constrained project scheduling problem with weighted earliness-tardinesss penalty costs. Project activities are assumed to have a known deterministic due date, a unit earliness as well as a unit tardiness penalty cost ...
Vanhoucke, Mario +2 more
core +2 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The energy scheduling problem: Industrial case-study and constraint propagation techniques [PDF]
This paper deals with production scheduling involving energy constraints, typically electrical energy. We start by an industrial case-study for which we propose a two-step integer/constraint programming method.
Pierre Lopez +5 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Servitization of Job Shop Scheduling Algorithms
The scheduling algorithm resources are not yet fully shared betwwen manufacturing execution system, and it is difficult to efficiently select the appropriate scheduling algorithm for scheduling problem from the candidate scheduling resources. To resolve
LIU Sheng-hui +3 more
doaj +1 more source
A novel class of scheduling policies for the stochastic resource-constrained project scheduling problem. [PDF]
We study the resource-constrained project scheduling problem with stochastic activity durations. We introduce a new class of scheduling policies for this problem, which make a number of a-priori sequencing decisions in a pre-processing phase, while the ...
Leus, Roel +2 more
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Machine Scheduling with Resource Dependent Processing Times [PDF]
We consider several parallel machine scheduling settings with the objective to minimize the schedule makespan. The most general of these settings is unrelated parallel machine scheduling.
Sviridenko,Maxim +2 more
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

