Results 71 to 80 of about 51,011 (258)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Adaptive scheduling strategy for cloud computing resources based on Q-learning algorithm

open access: yesMechanics & Industry
Given the frequently varying loads of virtual machines and swift variations in resource demand in a cloud computing environment, this article introduces an adaptive resource scheduling strategy model based on Q-learning.
Xu Jiaxing, Gao Xiaofei, Gao Ningyuan
doaj   +1 more source

Static scheduling in consideration of resource categories in collaborative product development project

open access: yesAdvances in Mechanical Engineering, 2015
In collaborative product development project plan phase, a reasonable allocation plan can shorten project duration. Static scheduling is a useful way to obtain the allocation result.
Yingzi Li, Shuo Zhang
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Customized Container Scheduling Strategy Based on GMM [PDF]

open access: yesJisuanji kexue
In cloud computing environments,as the number and types of containers continue to increase,resource management and scheduling complexity are increased.How to effectively schedule containers and optimize resource utilization and cluster perfor-mance has ...
ZHOU Kai, WANG Kai, ZHU Yuhang, PU Liming, LIU Shuxin, ZHOU Deqiang
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Data-Driven Evolutionary Resource Allocation for Vehicle–UAV Collaborative Inspection with Path-Scheduling Feedback

open access: yesTechnologies
To address the challenges of strong coupling between resource allocation and collaborative scheduling in vehicle–UAV cooperative inspections of power distribution lines, as well as the difficulty in balancing efficiency and stability, this paper proposes
Kunxiao Wu   +4 more
doaj   +1 more source

The Airfield Resource Scheduling Problem-Part Ⅱ:Development Status and Trends

open access: yesHangkong gongcheng jinzhan, 2019
Maximizing the utilization and benefit of airport resource has become a common goal of air transport stakeholders, including air navigation service providers, airports, airlines, passengers and governments.This work focuses on the development status and ...
Yin Jianan, Ma Yuanyuan, Hu Minghua
doaj   +1 more source

On Resource Efficiency of Workflow Schedules

open access: yesProcedia Computer Science, 2014
AbstractThis paper presents the Maximum Effective Reduction (MER) algorithm, which optimizes the resource efficiency of a workflow schedule generated by any particular scheduling algorithm. The inefficiency in resource usage of workflow execution/schedule is not only in the number of resources used, but also the actual amount of “used” resource time ...
Young Choon Lee   +2 more
openaire   +1 more source

Home - About - Disclaimer - Privacy