Results 121 to 130 of about 3,113,572 (297)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

A branch-and-bound procedure for the resource-constrained project scheduling problem with generalized precedence relations. [PDF]

open access: yes
We present an optimal procedure for the resource-constrained project scheduling problem (RCPSP) with generalized precedence relations (further denoted as RCPSP-GPR) with the objective of minimizing the project makespan. The RCPSP-GPR extends the RCPSP to
De Reyck, B, Herroelen, Willy
core  

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Timeslack-based techniques for generating robust projectschedules subject to resource uncertainty. [PDF]

open access: yes
The classical, deterministic resource-constrained project scheduling problem has been the subject of a great deal of research during the previous decades. This is not surprising given the high practical relevance of this scheduling problem. Nevertheless,
Lambrechts, Olivier   +2 more
core  

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

An investigation of resource-allocation decisions by means of project networks. [PDF]

open access: yes
This paper investigates the relationship between resource allocation and ES-policies, which are a type of scheduling policies introduced for stochastic scheduling and which can be represented by a directed acyclic graph.
Leus, Roel
core  

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