Results 71 to 80 of about 55,240 (258)

Information Leakage as a Scheduling Resource [PDF]

, 2017
High-security processes have to load confidential information into shared resources as part of their operation. This confidential information may be leaked (directly or indirectly) to low-security processes via the shared resource. This paper considers leakage from high-security to low-security processes from the perspective of scheduling. The workflow
Biondi, Fabrizio, Chadli, Mounir, Given-Wilson, Thomas, Legay, Axel   +3 more
openaire   +3 more sources

GPS: A Lightweight Greedy-Predictive Scheduling Approach for Energy-Aware Multi-Region Cloud Computing

Future Internet
Efficient resource allocation and task scheduling remain fundamental challenges in cloud computing because of resource heterogeneity, dynamic workload characteristics, and the increasing demand for scalable, energy-efficient, and sustainable cloud ...
Mohamed F. Yacoub, Ahmed E. Abdel Raouf, Walaa Gad, Nagwa L. Badr   +3 more
doaj   +1 more source

The Airfield Resource Scheduling Problem-Part Ⅱ:Development Status and Trends

Hangkong gongcheng jinzhan, 2019
Maximizing the utilization and benefit of airport resource has become a common goal of air transport stakeholders, including air navigation service providers, airports, airlines, passengers and governments.This work focuses on the development status and ...
Yin Jianan, Ma Yuanyuan, Hu Minghua
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Implementation determinants of a planned machine learning-enabled surgical scheduling system in a high-volume orthopaedic centre in Canada: qualitative findings

BMJ Open
Objectives Elective non-emergent surgical wait times have increased across countries such as Canada, straining operating room (OR) resources and affecting patient outcomes and healthcare spending.
Monika Kastner, Julie Makarski, Bheeshma Ravi, Aazad Abbas, Elias B Khalil, Cari M Whyne, Isabella Herrington, Divya Mathura, Johnathan R Lex   +8 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Resource allocation and scheduling in metasystems

, 1999
In this paper we present NWIRE, a new management architecture for metacomputing systems. After the general introduction of the architecture we first describe the properties that are relevant for scheduling. Then we derive general requirements for scheduling strategies in metasystems and point out differences to conventional job scheduling for parallel ...
Uwe Schwiegelshohn, Ramin Yahyapour
openaire   +3 more sources