Results 91 to 100 of about 3,113,572 (297)
Future InternetEfficient resource allocation and task scheduling remain fundamental challenges in cloud computing because of resource heterogeneity, dynamic workload characteristics, and the increasing demand for scalable, energy-efficient, and sustainable cloud ...
Mohamed F. Yacoub +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Stability and resource allocation in project planning. [PDF]
The majority of resource-constrained project scheduling efforts assumes perfect information about the scheduling problem to be solved and a static deterministic environment within which the pre-computed baseline schedule is executed.
Herroelen, Willy, Leus, Roel
core
Trust-aware dynamic level scheduling algorithm in cloud environment
Tongxin xuebao, 2014 Based on interpersonal trust model in sociology，a trust evaluation model is proposed based on users’ past experience with service provider，friends’ recommendations and third party’s feedback.By combining users’ trust requirement for service resource ...
Jie CAO +3 more
doaj +2 more sources
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
BMJ OpenObjectives Elective non-emergent surgical wait times have increased across countries such as Canada, straining operating room (OR) resources and affecting patient outcomes and healthcare spending.
Monika Kastner +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Proactive and reactive strategies for resource-constrained project scheduling with uncertain resource availabilities. [PDF]
Research concerning project planning under uncertainty has primarily focused on the stochastic resource-constrained project scheduling problem (stochastic RCPSP), an extension of the basic CPSP, in which the assumption of deterministic activity durations
Lambrechts, Olivier +2 more
core
Resource allocation and scheduling in metasystems
, 1999 In this paper we present NWIRE, a new management architecture for metacomputing systems. After the general introduction of the architecture we first describe the properties that are relevant for scheduling. Then we derive general requirements for scheduling strategies in metasystems and point out differences to conventional job scheduling for parallel ...
Uwe Schwiegelshohn, Ramin Yahyapour
openaire +3 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source