Results 91 to 100 of about 3,069,753 (207)
Exact and heuristic reactive planning procedures for multi-mode resource-constrained projects. [PDF]
The multi-mode resource-constrained project scheduling problem (MRCPSP) involves the determination of a baseline schedule of the project activities, which can be executed in multiple modes, satisfying the precedence relations and resource constraints ...
Deblaere, Filip +2 more
core
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Proactive resource allocation heuristics for robust project scheduling. [PDF]
The well-known deterministic resource-constrained project scheduling problem (RCPSP) involves the determination of a predictive schedule (baseline schedule or pre-schedule) of the project activities that satisfies the finish-start precedence relations ...
Braeckmans, Kristof +3 more
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Multidimensional Resource Task Scheduling Based on Particle Swarm Optimization in Edge Computing
IEEE AccessThe default Kubernetes scheduling algorithm, Balanced Resource Allocation (BRA), has limitations in achieving resource balance. It primarily focuses on the instantaneous utilization of CPU and memory while neglecting the coordinated optimization of disk ...
Zhonglu Zou +4 more
doaj +1 more source
An investigation of resource-allocation decisions by means of project networks. [PDF]
This paper investigates the relationship between resource allocation and ES-policies, which are a type of scheduling policies introduced for stochastic scheduling and which can be represented by a directed acyclic graph.
Leus, Roel
core
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Hierarchical Resource Management for Mega-LEO Satellite Constellation
SensorsThe mega-low Earth orbit (LEO) satellite constellation is pivotal for the future of satellite Internet and 6G networks. In the mega-LEO satellite constellation system (MLSCS), which is the spatial distribution of satellites, global users, and their ...
Liang Gou +6 more
doaj +1 more source