Results 51 to 60 of about 2,284,877 (259)

Den‐site characteristics and selection by brown bears (Ursus arctos) in the central Brooks Range of Alaska

open access: yesEcosphere, 2019
Selection and use of dens is a critical behavioral adaption of bears (Ursus spp.) to survive extended periods of resource limitation. We analyzed selection of den sites by brown bears (Ursus arctos) in an arctic montane environment from 2014 to 2017.
Mathew S. Sorum   +5 more
doaj   +1 more source

Deep Learning Based Resource Availability Prediction for Local Mobile Crowd Computing

open access: yesIEEE Access, 2021
Mobile crowd computing (MCC) that utilizes public-owned (crowd’s) smart mobile devices (SMDs) collectively can give adequate computing power without any additional financial and ecological cost.
Pijush Kanti Dutta Pramanik   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

IMPROVEMENT MANAGEMENT OF TEACHER RESOURCE AMONG VOCATIONAL HIGH SCHOOL BASED ON INTERNATIONAL STANDARD SCHOOL INVEST (INDONESIA VOCATIONAL EDUCATION STRENGTHENING) IN YOGYAKARTA [PDF]

open access: yes, 2012
This education research aimed to: (1) find an overview of resource about teacher’s resource improvement management in vocational high school based on international INVEST in Yogyakarta, (2) find the effectiveness for the implementation of quality ...
Dian Rustamana Indra Putra, Dian Rustamana Indra Putra
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Home Range and Habitat Selection of Feral Horses (Equus ferus f. caballus) in a Mountainous Environment: A Case Study from Northern Greece

open access: yesLand
The spatial ecology of feral horses (Equus ferus f. caballus) in Greece has never been studied before, including home range size and habitat selection. We tracked two mares fitted with global positioning system collars between September 2020 and August ...
Dimitrios E. Bakaloudis   +6 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Optimal Resource Allocation and Relay Selection in Bandwidth Exchange Based Cooperative Forwarding [PDF]

open access: yes, 2012
In this paper, we investigate joint optimal relay selection and resource allocation under bandwidth exchange (BE) enabled incentivized cooperative forwarding in wireless networks.
Islam, Muhammad Nazmul   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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