Results 151 to 160 of about 12,337,601 (330)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Respect Defended

open access: yesTrends in Cognitive Sciences, 2019
Engelmann, Jan M., Tomasello, Michael
openaire   +3 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Ramifications of generalized Feller theory. [PDF]

open access: yesJ Evol Equ
Cuchiero C, Möllmann T, Teichmann J.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Patients' experiences of obstetric and gynaecological care in Québec: interactions with healthcare providers, respect of rights, satisfaction, and trust in the healthcare system. [PDF]

open access: yesHealth Psychol Behav Med
Lévesque S   +7 more
europepmc   +1 more source

Tempered and Hadamard-Type Fractional Calculus with Respect to Functions

open access: yesMediterranean Journal of Mathematics, 2019
Hafiz Muhammad Fahad   +3 more
semanticscholar   +1 more source

pride versus self-respect [PDF]

open access: yes, 2017
Morton, Adam
core  

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