Results 161 to 170 of about 10,970,352 (296)

Correction: Prediction of the ectasia screening index from raw Casia2 volume data for keratoconus identification by using convolutional neural networks. [PDF]

PLoS One
Mirsalehi M, Fassbind B, Streich A, Langenbucher A.   +3 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

PSEUDOSCORPIONES), FROM TURKEY AND MACEDONIA (FYROM), RESPECTIVELY

, 2014
— Two new species of endemic and relict cave-dwellers of genus Neobisium Chamberlin, have been described from Turkey and Macedonia (FYROM), respectively. From its phеnetically close congener, N. granulatum Beier, N. yozgati n. sp.
M. Aktaş, H. Demir
core  

Noise quantification in the intensive care unit of a tertiary care hospital. [PDF]

World J Crit Care Med
Gupta R, Chadha AS, Lakra H, Rehan R, Kalra R, Ray S.   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Adenosine and 1,N⁶-Ethenoadenosine-Derived Nucleolipids: Synthesis, Lipophilicity (log<i>P</i>), and Cytotoxic Activity Compared to Conventional Cytostatics in Glioma and Glioblastoma Cell Lines. [PDF]

Int J Mol Sci
Lünswilken M, Bender-Arnst E, Barakat F, Leinweber E, Beginn U, Bonaterra GA, Kinscherf R.   +6 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Consumer Behavior Toward Nonlocal Brands

The Lahore Journal of Business
This study explores consumer behavior toward nonlocal brands in Pakistan. Specifically, it examines the extent to which (i) product quality, (ii) country of origin, (iii) religiosity (in the context of Pakistan as a predominantly Muslim country), (iv ...
Sana Aza, Amina Talat, Feryal Khan, Anam Rana   +3 more
doaj  

Ultrastable green top-emitting OLEDs approaching BT.2020 enabled by narrowband phosphorescent emitters. [PDF]

Sci Adv
Zhan F, Yuan Y, Xu K, Wu K, She Y, Li G.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source