Results 181 to 190 of about 10,970,352 (296)
NToxSEM: Enhancing prediction of neurotoxic peptides and neurotoxins using a stacked ensemble-based multimodal framework. [PDF]
Protein SciShoombuatong W +3 more
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Smallholder Income Diversification in Zambia: The Way Out of Poverty?
1) One can achieve poverty reduction in rural areas of Zambia by both growth and inequality reduction, but growth must be the main driver; 2) Rural income growth does not come from agriculture alone so options to diversify income are very important and ...
Bigsten, Arne, Tengstam, Sven
core
Apple Market Integration: Implications for Sustainable Agricultural Development
Lahore Journal of EconomicsIn a market driven economy, price signals guide and regulate production, consumption and marketing decisions over time, form and place. Identifying the causes of price differences in interregional or spatial markets has therefore become an important ...
Abdul Gafoor, Maula Dad, Khalid Mushtaq
doaj
Association mapping for hop cone chemistry and morphology identifies natural beneficial allele stacks. [PDF]
Plant GenomeClare SJ, Schmuker P, Altendorf K.
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
3D object detection for vehicle-mounted LiDAR based on deep learning and euclidean clustering algorithm. [PDF]
PLoS OneZhang N, Xi M, Fang J, Wang F.
europepmc +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source