Results 191 to 200 of about 10,970,352 (296)

Thermodynamic coupling between cold and heat activations of TRPV2. [PDF]

Sci Rep
Wang G.
europepmc   +1 more source

Respect for Muscle [PDF]

Sleep, 2012
Donald L, Bliwise, David B, Rye
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Quinoid-controlled bond-length alternation enables high-mobility non-fused π-conjugated polymers. [PDF]

Chem Sci
Mikie T, Iguchi K, Kamimura R, Tanaka K, Ishii H, Osaka I.   +5 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Photochemical processes developed in composites based on MoS₂, poly(<i>ortho</i>-toluidine), and reduced graphene oxide. [PDF]

Nanoscale Adv
Cercel M, Nila A, Smaranda I, Androne A, Burlanescu T, Lörinczi A, Negrila C, Matei E, Baibarac M.   +8 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

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, 1995
H. D'Hauteville, P.J. Sansonetti, M.‐F. Carlier, J.‐B. Marchand, E. Gouin, C. Kocks, P. Cossart   +6 more
core   +1 more source

Optimizing Ecological Restoration in Alpine Mining Areas Through Fertilization and Seeding-Rate Management: Insights from Vegetation-Soil Stoichiometry. [PDF]

Plants (Basel)
Hu N, Wang X, Song M, Jiang F, Qi K, Li Z.   +5 more
europepmc   +1 more source