Results 81 to 90 of about 12,123,779 (244)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Mortgage finance in central and eastern Europe -- opportunity or burden ? [PDF]

open access: yes
Household credit, especially for mortgages, has doubled over the past years in the new European Union member countries, raising concerns about the economic and social consequences of household indebtedness in the event of a macroeconomic crisis.
Tiongson, Erwin   +2 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Trial schematic for the study and test phases respectively.

open access: yes, 2013
Trial schematic for the study and test phases respectively.
Eric D. Leshikar (320876)   +2 more
core   +1 more source

Cold ‘Brooks’ cherries suffer more pitting and bruising

open access: yesCalifornia Agriculture, 1994
The incidence of pitting and impact bruising on ‘Brooks’ sweet cherries was greatest when the flesh temperature was near 1 °C (34°F), intermediate near 10°C (50°F), and lowest near 20°C (68°F).
Carlos Crisosto   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Quantitative comparison results, ↑ and ↓ indicate larger and smaller, respectively.

open access: yes
Quantitative comparison results, ↑ and ↓ indicate larger and smaller, respectively.
Cheng Zhang (70708)   +3 more
core   +1 more source

Serum cinnamoylglycine (interaction effect, P = 0.0017; group contrasts immediately- and 14-h-post-exercise, P = 0.008 and 0.009, respectively; Q = 0.1421 and 0.265, respectively).

open access: yes, 2013
Serum cinnamoylglycine (interaction effect, P = 0.0017; group contrasts immediately- and 14-h-post-exercise, P = 0.008 and 0.009, respectively; Q = 0.1421 and 0.265, respectively).
Amy M. Knab (322666)   +6 more
core   +1 more source

Evidence for a new species of whitefly: UCR findings and implications

open access: yesCalifornia Agriculture, 1993
The whitefly that caused over $500 million in damage to U.S. agricultural production in 1991 initially was referred to as a strain of sweetpotato whitefly.
Thomas Perring   +4 more
doaj   +1 more source

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