Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo +7 more
wiley +1 more source
High-fidelity crop modelling: innovations driving sustainable fruit horticulture. [PDF]
Das U +4 more
europepmc +1 more source
Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins
Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller +2 more
wiley +1 more source
Editorial: Current developments in artificial organs and engineered <i>ex-situ</i> perfused organs. [PDF]
Amarelli C +3 more
europepmc +1 more source
Enviromics and Abiotic Enviromics: Enhancing Stress Biology and Plant Resilience Breeding
Environmental stressors are captured through high‐throughput envirotyping and integrated into an enviromic framework with genomic, transcriptomic, phenomic, and environmental data. AI/ML models enable prediction and guide marker‐assisted selection, genomic selection, genome editing, and gene pyramiding toward improved abiotic stress tolerance, yield ...
Guangchao Sun +6 more
wiley +1 more source
Life Cells for future energy systems: adaptation, evolution and exploration. [PDF]
Lai J, Zhang F, Li L, Wu F, Chen R.
europepmc +1 more source
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source
Sedation is not sleep: changes in airway physiology during deep sedation and the duty to rescue. [PDF]
Kim S.
europepmc +1 more source
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang +10 more
wiley +1 more source
The "ABCD" framework for assessment: a task-oriented approach to reconcile multimodal diagnostic discordance. [PDF]
Mijiti W, Apaer S, Han X, Dong Q, Cao X.
europepmc +1 more source

