Results 61 to 70 of about 66,640 (250)

Shari`ah, Brain Death, and Organ Transplantation

American Journal of Islam and Society, 2005
Introduction In the early 1980s, comprehensive developments in the public health system as well as markedly improved possibilities for organ transplantation due to the introduction of immune suppressants,2 namely, the artificial prevention of organ ...
Johannes Grundmann
doaj   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Characteristics of mechanical ventilation in patients of an intensive care unit

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: non-invasive mechanical ventilation (NIMV) has been on the increase during the last decades. The specialized literature reveals its undeniable success in medical care of seriously ill patients.
Gilberto Lázaro Betancourt-Reyes
doaj  

Influence of drainage status on soil and water chemistry, litter decomposition and soil respiration in central Amazonian forests on sandy soils

Revista Ambiente & Água, 2011
Central Amazonian rainforest landscape supports a mosaic of tall terra firme rainforest and ecotone campinarana, riparian and campina forests, reflecting topography-induced variations in soil, nutrient and drainage conditions.
Antônio Ocimar Manzi, Flávio Jesus Luizão, Marcos Alexandre Bolson, Bart Kruijt, Jurgen Kesselmeier, Margriet Groenendijk, Maarten Johannes Waterloo, Albertus Johannes Dolman, Fabrício Berton Zanchi   +8 more
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Longitudinal Respiratory Subphenotypes and Differences in Response to Positive End-Expiratory Pressure and Fio2 Ventilation Strategy in COVID-19 ARDSTake-Home Points

CHEST Critical Care
Background: In patients with ARDS, positive end-expiratory pressure (PEEP) titration remains a challenge and recommendations are not in agreement.
Robin L. Goossen, MD, Daan F.L. Filippini, MD, Relin van Vliet, MD, Laura A. Buiteman-Kruizinga, RN, PhD, Markus W. Hollmann, MD, PhD, Sheila N. Myatra, MD, Ary Serpa Neto, MD, PhD, Peter E. Spronk, MD, PhD, Meta C.E. van der Woude, MD, PhD, Marcus J. Schultz, MD, PhD, David M.P. van Meenen, MD, PhD, Frederique Paulus, PhD, Lieuwe D.J. Bos, MD, PhD   +12 more
doaj   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Factors related to mortality of senior citizens due to pneumonia associated to mechanical ventilation

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2018
Background: at the intensive care unit of the “Dr. Agostinho Neto” Hospital a way to assess the risk of mortality of senior citizens due to pneumonia associated to mechanical ventilation is not available.Objective: to identify the factors related to ...
Reinaldo Elias-Sierra, Karla Sucet Elias-Armas, Javier Pérez-Capdevila, Rodney Vargas-Alonso   +3 more
doaj  

Comparative Study between Surgical Repair of Atrial Septal Defect via Median Sternotomy, Right Submammary Thoracotomy, and Right Vertical Infra-Axillary Thoracotomy

Brazilian Journal of Cardiovascular Surgery
Objective: To compare the results of surgical repair via median sternotomy, right submammary thoracotomy, and right vertical infra-axillary thoracotomy for atrial septal defect (ASD).
Zeng-rong Luo, Qiang Chen, Ling-li Yu, Liang-wan Chen, Zhong-yao Huang   +4 more
doaj   +1 more source