Results 141 to 150 of about 1,077,039 (388)

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang   +7 more
wiley   +1 more source

Translating a Preclinically Tested 15 Hz rTMS Protocol to Humans With Chronic Spinal Cord Injury: A Safety and Feasibility Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat   +8 more
wiley   +1 more source

Medication Use in Multiple Sclerosis: A Population‐Based Comparison With the General Danish Population

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen   +4 more
wiley   +1 more source

Letter to the Editor Regarding: “Association between Metabolic Score for Insulin Resistance (METS-IR) and Risk of Obstructive Sleep Apnea: Analysis of NHANES Database and a Chinese Cohort” [Letter]

open access: yesNature and Science of Sleep
Qing-qing Shan, Yangke Li Department of Respiration, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu, 610095, People’s Republic of ChinaCorrespondence: Qing-qing Shan, Department of Respiration, Chengdu Integrated TCM & ...
Shan QQ, Li Y
doaj  

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald   +74 more
wiley   +1 more source

Normal Respiration and Intramolecular Respiration [PDF]

open access: yesThe American Naturalist, 1901
"RESPIRATION is essentially the intake of oxygen and the output of carbon-dioxide by living cells. In the higher animals two phases of respiration are distinguished the exter-nal, the exchange of gases between the air or water and the blood; and the internal, the exchange between the blood, lymph, and the tissues." I In plants there is, for the most ...
openaire   +2 more sources

A Comparison of Urban Soil to Rural Soils [PDF]

open access: yes, 2017
Previous studies have shown significantly more seedlings and saplings at control sites above Estacada, Oregon than in Forest Park. In an attempt to determine possible reasons for the lack of young trees in the urban forest, we measured the depth of the O
Broshot, Nancy   +3 more
core   +1 more source

SYHA1813, A VEGFR and CSF1R Inhibitor, in Patients With Recurrent High‐Grade Gliomas: A Multicenter, Open‐Label Phase I Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy