Results 311 to 320 of about 1,062,445 (387)

Postnatal development in the cold render bird mitochondria more susceptible to heat stress. [PDF]

Proc Biol Sci
Correia M, Thoral E, Persson E, Chamkha I, Elmér E, Nord A.   +5 more
europepmc   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

RAGE Knockout Mitigates Diet-Induced Obesity and Metabolic Disruption. [PDF]

Metabolites
Palmer IL, Parker G, Chiu AT, Beus CG, Evans EP, Radford JH, Braithwaite CR, van Slooten RD, Cooper-Leavitt ET, Moore ZE, Clarke DM, Parrish RR, Arroyo JA, Reynolds PR, Bikman BT.   +14 more
europepmc   +1 more source

A Hydro‐Expansive and Degradable Biomaterial Enabling Shape Recovery of Film‐Based Devices in Biofluids

Advanced Materials, EarlyView.
A chitosan‐based bio‐composite exhibits stable and strong tensile strength during volumetric expansion in body fluids, serving as a functional coating that enables a thin film‐based device to self‐flatten from its tubular shape required for catheter delivery.
Ruoxing Wang, Jiajie Sui, Pengfei Chen, Zulmari Silva‐Pedraza, Jack Bontekoe, Jooyong Kim, Patrick Li, Fengdan Pan, Eric G. Schmuck, Satoru Osaki, Bo Liu, Xudong Wang   +11 more
wiley   +1 more source

A constricted mitochondrial morphology formed during respiration. [PDF]

Nat Commun
Singh MK, Cavellini L, Morcillo-Parra MA, Kunz C, Lelek M, Bomme P, Barascu A, Alsayyah C, Teixeira MT, Belgareh-Touzé N, Mallet A, Dietrich L, Zimmer C, Cohen MM.   +13 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

ATP synthase inhibition, an overlooked confounding factor in the mitochondrial stress test. [PDF]

PLoS One
Corbin J, Lehoux EA, Catelas I.
europepmc   +1 more source

An Anti‐Myd88 Peptide Synergistically Enhances the Anti‐Inflammatory Effects of Extracellular Vesicles from Naïve Umbilical Cord MSC or HEK293F CD24 Overexpressing Cells

Advanced Materials Interfaces, EarlyView.
This study confirms that extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) or HEK293F cells overexpressing CD24 have anti‐inflammatory effects in macrophages and monocytes. Further loading either of these EVs with an anti‐Myd88 peptide synergistically enhanced the anti‐inflammatory effects of the EVs.
Burçin İrem Abas, Markus Bergqvist, Lijuan Yu, Yi Wang, Mario Gimona, Kyong‐su Park, Jan Lötvall   +6 more
wiley   +1 more source

Altered Mitochondrial Respiration Is Associated With Loss of Nuclear-Encoded OXPHOS Genes in Parasitic Broomrapes. [PDF]

Ecol Evol
Cai L, Jansen RK, Havird JC.
europepmc   +1 more source