Results 41 to 50 of about 488,792 (318)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Lymphangiomatosis with pulmonary, mediastinal, and spinal involvement in a pediatric patient: a case report

BMC Pediatrics
Background Lymphangiomatosis is a rare disorder characterized by abnormal proliferation and dilation of lymphatic vessels, resulting in non-specific clinical manifestations.
Yuxing Sun, Jun Zhou, Xiaoqin Hu, Ming Li, Li Tan   +4 more
doaj   +1 more source

Respiration-gated imaging in bleomycin induced fibrosis.

, 2023
(A) microCT images from a respiration-gated scan of a saline and a bleomycin-instilled mouse 3 weeks post-instillation imaged on a Bruker Skyscan 1276 at 35 μm resolution.
Annette Robichaud (3010194), Lindsay T. McDonald (4237120), Ali N. Bahadur (14593108), Elizabeth F. Redente (14593102), Lennart K. Lundblad (14593111), Katrina W. Kopf (14593105)   +5 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Amelioration of Oxidative Stress in Rats with Chronic Obstructive Pulmonary Disease through Shenqi Huatan Decoction Activation of Peroxisome Proliferator-Activated Receptor Gamma-Mediated Activated Protein Kinase/Forkhead Transcription Factor O3a Signaling Pathway

Canadian Respiratory Journal
Background. Chronic obstructive pulmonary disease (COPD) is a common respiratory disease. Currently, no specific treatment strategy has been established; therefore, finding new treatment methods is essential. Clinically, Shenqi Huatan Decoction (SQHT) is
Jingjing Chen, Wenxiao Qiao, Xiaoming Xue, Dian Li, Ye Zhang, Di Xie, Jinyun Wang, Yaoqin Sun, Shuo Yang, Zhuomin Yang   +9 more
doaj   +1 more source

Isoliquiritigenin Activates Nuclear Factor Erythroid-2 Related Factor 2 to Suppress the NOD-Like Receptor Protein 3 Inflammasome and Inhibits the NF-κB Pathway in Macrophages and in Acute Lung Injury

Frontiers in Immunology, 2017
Among the cellular response mechanisms, the nuclear factor erythroid-2 related factor 2 (Nrf2) pathway is considered a survival pathway that alleviates oxidative injury, while both the NOD-like receptor protein 3 (NLRP3) and NF-κB pathways are pro ...
Qinmei Liu, Hongming Lv, Zhongmei Wen, Xinxin Ci, Liping Peng   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation for Clinical Applications in Neurological and Psychiatric Disorders: An Overview

Eurasian Journal of Medicine, 2019
Neurological and psychiatric disorders are characterized by several disabling symptoms for which effective, mechanism-based treatments remain elusive. Consequently, more advanced non-invasive therapeutic methods are required.
Sergio Machado, Adriana Cardoso Silva, Leonardo Ferreira Almada, Tamires Marinho, Felipe Novaes, Leonardo Caixeta, Renata Teles Vieira, Flávia Paes, Oscar Arias-Carrión, Antonio Egidio Nardi   +9 more
doaj   +1 more source

Association of PM2.5 and PM10 with Acute Exacerbation of Chronic Obstructive Pulmonary Disease at lag0 to lag7: A Systematic Review and Meta-Analysis

COPD, 2022
This study aimed to conduct a meta-analysis to investigate whether short-term exposure to fine (PM2.5) and coarse (PM10) particulate matter was associated with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) hospitalization ...
Niuniu Li, Jianling Ma, Kun Ji, Liyun Wang   +3 more
doaj   +1 more source

A new concept for modelling the moisture dependence of heterotrophic soil respiration

, 2023
The moisture dependence of heterotrophic soil respiration is a key factor affecting the uncertainty in predicting the response of soil organic carbon (SOC) to global warming.
Pengfei Huang, Yuan Liu, Huang, P., Zhongdong Huang, Zhongyang Li, Li, Z., Liu, Y., Xiaoxian Zhang, Zhang, X., Huang, Z.   +9 more
core   +1 more source