Results 61 to 70 of about 552,573 (310)

Amelioration of Oxidative Stress in Rats with Chronic Obstructive Pulmonary Disease through Shenqi Huatan Decoction Activation of Peroxisome Proliferator-Activated Receptor Gamma-Mediated Activated Protein Kinase/Forkhead Transcription Factor O3a Signaling Pathway

open access: yesCanadian Respiratory Journal
Background. Chronic obstructive pulmonary disease (COPD) is a common respiratory disease. Currently, no specific treatment strategy has been established; therefore, finding new treatment methods is essential. Clinically, Shenqi Huatan Decoction (SQHT) is
Jingjing Chen   +9 more
doaj   +1 more source

Repetitive Transcranial Magnetic Stimulation for Clinical Applications in Neurological and Psychiatric Disorders: An Overview

open access: yesEurasian Journal of Medicine, 2019
Neurological and psychiatric disorders are characterized by several disabling symptoms for which effective, mechanism-based treatments remain elusive. Consequently, more advanced non-invasive therapeutic methods are required.
Sergio Machado   +9 more
doaj   +1 more source

Extensive prokaryotic maintenance respiration in the sea influenced by osmoregulation

open access: yes, 2023
Microbial respiration is the major process consuming oxygen in the biosphere. The relative energy demand from growth of biomass or maintenance activities determines the regulation of respiration with impact on how the development of hypoxia and CO2 ...
Wikner, Johan,   +5 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Association of dietary caffeine intake and metabolites in the urine of individuals with latent tuberculosis infection: a cross-sectional study

open access: yesBMC Pulmonary Medicine
Background Currently, there is insufficient evidence available regarding the association between dietary caffeine intake and latent tuberculosis infection (LTBI).
Yangke Li   +7 more
doaj   +1 more source

Clinical Features of EGFR Double Mutation in Non-small Cell Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2018
Background and objective The clinical features of patients with common single-mutation of epidermal growth factor receptor (EGFR) in non-small cell lung cancer (NSCLC) has been well characterized.
Mengyao WANG   +4 more
doaj   +1 more source

Substrates used in SIR assays can inhibit basal respiration in rewetted soil [PDF]

open access: yes, 2010
Respiration assays are routinely used for investigating microbial metabolic activity in soil, but usually after a period of "conditioning" whereby dry soil is rewetted and incubated for a period of days.
Archibald, R.   +3 more
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Nomogram for Predicting Efficacy and Prognosis After Chemotherapy for Advanced NSCLC

open access: yesThe Clinical Respiratory Journal
Purpose One major issue is the therapeutic effect following chemotherapy for non–small cell lung cancer (NSCLC). Although numerous risk factors have been identified and novel therapies have been developed, improving patient overall survival (OS) remains ...
Jiaying Gao   +6 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

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