Results 61 to 70 of about 552,573 (310)
Background. Chronic obstructive pulmonary disease (COPD) is a common respiratory disease. Currently, no specific treatment strategy has been established; therefore, finding new treatment methods is essential. Clinically, Shenqi Huatan Decoction (SQHT) is
Jingjing Chen +9 more
doaj +1 more source
Neurological and psychiatric disorders are characterized by several disabling symptoms for which effective, mechanism-based treatments remain elusive. Consequently, more advanced non-invasive therapeutic methods are required.
Sergio Machado +9 more
doaj +1 more source
Extensive prokaryotic maintenance respiration in the sea influenced by osmoregulation
Microbial respiration is the major process consuming oxygen in the biosphere. The relative energy demand from growth of biomass or maintenance activities determines the regulation of respiration with impact on how the development of hypoxia and CO2 ...
Wikner, Johan, +5 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Background Currently, there is insufficient evidence available regarding the association between dietary caffeine intake and latent tuberculosis infection (LTBI).
Yangke Li +7 more
doaj +1 more source
Clinical Features of EGFR Double Mutation in Non-small Cell Lung Cancer
Background and objective The clinical features of patients with common single-mutation of epidermal growth factor receptor (EGFR) in non-small cell lung cancer (NSCLC) has been well characterized.
Mengyao WANG +4 more
doaj +1 more source
Substrates used in SIR assays can inhibit basal respiration in rewetted soil [PDF]
Respiration assays are routinely used for investigating microbial metabolic activity in soil, but usually after a period of "conditioning" whereby dry soil is rewetted and incubated for a period of days.
Archibald, R. +3 more
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Nomogram for Predicting Efficacy and Prognosis After Chemotherapy for Advanced NSCLC
Purpose One major issue is the therapeutic effect following chemotherapy for non–small cell lung cancer (NSCLC). Although numerous risk factors have been identified and novel therapies have been developed, improving patient overall survival (OS) remains ...
Jiaying Gao +6 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source

