Acute Respiratory Emergencies in Pediatrics
This resource is designed as a simulation exercise. It is one of a series of exercises utilized for education and training about pediatric emergencies for residents, nurses, and prehospital providers. It can be utilized for education or for assessment of
Sharon Calaman, Christopher Haines
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Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
The functional overlap between respiration and global signal and its behavioral relevance
Resting-state fMRI studies encounter the challenge of interpreting fluctuations in the global signal (GS). The GS has been linked to arousal, vigilance states, cognition, and psychiatric disorders, suggesting its functional relevance.
Jing Yuan, Yuejia Luo, Jianfeng Zhang
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CLINICAL MEANING OF LACTATE CONCENTRATION STUDYING IN NEWBORNS IN THE CRITICAL STATE
The article presents the outcomes of studying lactate concentration depending on clinical laboratory status in newborns in critical state. The study included 128 newborns with body mass of 1500 (1300-1740) gr. and gestation period 30.5 (29-32) weeks.
K. V. Pshenisnov +3 more
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Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper +25 more
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Respiratory physiotherapy techniques used in patients with neurological disease
Breathing and its disorders are in the centre of interest of many medical and healthcare specialists. Paresis or loss of strength of skeletal muscles may often be observed in patients with neurological disease.
Daniela Botiková
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ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
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A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
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Influence of the speech-language pathologist’s orientation on maximum phonation times
Purpose: to compare the results of maximum phonation times (MPTs) under two different forms of speech-language pathology orientation to extract these measures. Methods: 60 women between 17 and 23 years divided equally into two groups participated: Study
Amanda Rissetti Coelho +4 more
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Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
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