Results 31 to 40 of about 3,346,625 (362)

LncRNA H19 governs mitophagy and restores mitochondrial respiration in the heart through Pink1/Parkin signaling during obesity

open access: yesCell Death and Disease, 2021
Maintaining proper mitochondrial respiratory function is crucial for alleviating cardiac metabolic disorders during obesity, and mitophagy is critically involved in this process.
Shaohua Wang   +14 more
semanticscholar   +1 more source

Mitochondrial disorders of the OXPHOS system

open access: yesFEBS Letters, 2020
Mitochondrial disorders are among the most frequent inborn errors of metabolism, their primary cause being the dysfunction of the oxidative phosphorylation system (OXPHOS).
E. Fernández‐Vizarra, M. Zeviani
semanticscholar   +1 more source

Self-Regulation of Breathing as a Primary Treatment for Anxiety [PDF]

open access: yes, 2015
Understanding the autonomic nervous system and homeostatic changes associated with emotions remains a major challenge for neuroscientists and a fundamental prerequisite to treat anxiety, stress, and emotional disorders.
Barnes, Vernon A.   +3 more
core   +1 more source

A Comparative Study of ECG-derived Respiration in Ambulatory Monitoring using the Single-lead ECG

open access: yesScientific Reports, 2020
Cardiorespiratory monitoring is crucial for the diagnosis and management of multiple conditions such as stress and sleep disorders. Therefore, the development of ambulatory systems providing continuous, comfortable, and inexpensive means for monitoring ...
C. Varon   +12 more
semanticscholar   +1 more source

Inborn disorders of the malate aspartate shuttle

open access: yesJournal of Inherited Metabolic Disease, 2021
Over the last few years, various inborn disorders have been reported in the malate aspartate shuttle (MAS). The MAS consists of four metabolic enzymes and two transporters, one of them having two isoforms that are expressed in different tissues. Together
M. Broeks   +4 more
semanticscholar   +1 more source

Evidence for detrimental cross interactions between reactive oxygen and nitrogen species in Leber's hereditary optic neuropathy cells [PDF]

open access: yes, 2015
Here we have collected evidence suggesting that chronic changes in the NO homeostasis and the rise of reactive oxygen species bioavailability can contribute to cell dysfunction in Leber’s hereditary optic neuropathy (LHON) patients.We report that ...
Arese, Marzia   +12 more
core   +9 more sources

Protocol of the SOMNIA project : an observational study to create a neurophysiological database for advanced clinical sleep monitoring [PDF]

open access: yes, 2019
Introduction Polysomnography (PSG) is the primary tool for sleep monitoring and the diagnosis of sleep disorders. Recent advances in signal analysis make it possible to reveal more information from this rich data source.
Arsenali, Bruno   +16 more
core   +2 more sources

Modelling postharvest quality behaviour as affected by preharvest conditions [PDF]

open access: yes, 2003
Some hundred years ago, wise men decided that preharvest research and applications had to be regarded separated from the postharvest handling and behaviour. Over the years, both areas developed completely separated.
Heuvelink, E.   +3 more
core   +2 more sources

Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice

open access: yesMolecular Metabolism, 2022
Objective: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and myopathy associated with ...
Patrick M. Schaefer   +8 more
doaj   +1 more source

Significance of Heme and Heme Degradation in the Pathogenesis of Acute Lung and Inflammatory Disorders

open access: yesInternational Journal of Molecular Sciences, 2021
The heme molecule serves as an essential prosthetic group for oxygen transport and storage proteins, as well for cellular metabolic enzyme activities, including those involved in mitochondrial respiration, xenobiotic metabolism, and antioxidant responses.
S. Ryter
semanticscholar   +1 more source

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