Results 81 to 90 of about 1,167,422 (304)

Adaptation to Respiratory Acidosis in the Turtle Bladder

Experimental Biology and Medicine, 1990
The effect of in vivo respiratory acidosis for 4 and 48 hr was examined in the turtle bladder by placing turtles in hypercapnic chambers. Blood pH was significantly lowered and pCO2 was significantly elevated over control values both 4 and 48 hr, while blood bicarbonate was only increased after 48 hr.
Daniel Kniaz, Jose A.L. Arruda
openaire   +3 more sources

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou, Yu Wu, Guoran Li, Yongwen Qin, Man Qi, Zhitao Jin   +5 more
wiley   +1 more source

Things We Do for No Reason™: Arterial blood gas testing to screen for hypercarbic respiratory failure

Journal of Hospital Medicine, EarlyView.
Abstract Venous blood gases (VBGs) are safe and effective at screening for hypercarbic respiratory failure. Multiple studies have validated that a VBG with a PvCO2 less than 45 reliably rules out hypercarbia. The use of VBGs for the initial screening of hypercarbia when hypercarbic respiratory failure is suspected can reduce the overall use of arterial
Mary E. Lacy, Lisa Saa, Zachary Bruss, Leonard Noronha   +3 more
wiley   +1 more source

Extremely Rare Neonatal Case With Pyloric Atresia, Heart Defects, Hypotonia, Jaundice, and Acidosis. [PDF]

Clin Case Rep
ABSTRACT Pyloric atresia (PA) is an exceptionally rare congenital cause of gastric outlet obstruction, often associated with syndromic conditions such as epidermolysis bullosa (EB). This case highlights a diagnostically challenging presentation of *non‐syndromic pyloric atresia* in a neonate, complicated by a moderate mid‐muscular ventricular septal ...
Abouodeh S, Alshami Y, Hroub O, Hroub M, Hammouri AG, Shaltaf A, Shihadeh W, Dawod N.   +7 more
europepmc   +2 more sources

Cardiogenic shock requiring VA‐ECMO therapy in scorpionism‐induced myocarditis

ESC Heart Failure, EarlyView.
Alba I. Violino, María Alicia Lozano, Rocio Garcia Moralez, Juan P. Ricarte‐Bratti, Julieta Lozita, Elizabeth Y. Ravinovich   +5 more
wiley   +1 more source

Successful perioperative management of living-donor liver transplantation for a patient with severe methylmalonic acidemia: a case report

JA Clinical Reports, 2018
Background Methylmalonic acidemia (MMAemia) is a rare hereditary disease affecting organic acid metabolism. It causes recurrent metabolic acidosis and secondary mitochondrial dysfunction, resulting in a poor prognosis. Liver transplantation (LT) has been
Akiko Hirotsu, Eriko Kusudo, Natsumi Mori, Yoshimitsu Miyai, Kengo Suzuki, Shuji Kawamoto, Kazuhiko Fukuda   +6 more
doaj   +1 more source

Breathing and balance: Clinical insights and management strategies of respiratory acid-base disorders. [PDF]

Nutr Clin Pract
Abstract Respiratory acidosis and alkalosis are two of the four main acid‐base processes encountered in clinical practice. These two processes are tightly balanced by breathing. Identification and management of respiratory acid‐base disorders are important for clinicians, particularly when caring for patients with underlying pulmonary and neurological ...
Tucker AM, Johnson TN.
europepmc   +2 more sources

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Orexin Neurons Contribute to Central Modulation of Respiratory Drive by Progestins on ex vivo Newborn Rodent Preparations

Frontiers in Physiology, 2019
Dysfunction of central respiratory CO2/H+ chemosensitivity is a pivotal factor that elicits deep hypoventilation in patients suffering from central hypoventilation syndromes. No pharmacological treatment is currently available.
Camille Loiseau, Alexis Casciato, Besma Barka, Florence Cayetanot, Laurence Bodineau   +4 more
doaj   +1 more source

Role of the DPP4 Receptor in SARS‐CoV Entry: Insights From Docking and Molecular Dynamics Simulations

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein–receptor interactions play a critical role in viral entry and pathogenesis. While ACE2 is the primary receptor for SARS‐CoV, the role of DPP4 as potential coreceptor remains underexplored. This study investigates the binding mechanisms and dissociation dynamics of the SARS‐CoV/DPP4, SARS‐CoV/ACE2 and MERS‐CoV/DPP4 complexes using ...
Patrícia Pereira Duzi Carvalho, Nelson Augusto Alves   +1 more
wiley   +1 more source